This book describes the development of two kinds of continuous-flow transformation using heterogeneous catalysts, and explains how they can be applied in the multistep synthesis of active pharmaceutical ingredients. It demonstrates and proves that fine chemicals can be synthesized under continuous-flow conditions using heterogeneous catalysis alone. Importantly, the book also proposes a general concept and strategy for achieving multistep flow synthesis and developing heterogeneous catalysts, and shows that commercially available anion exchange resin can be used as a water-tolerant strong base catalyst for various types of continuous-flow aldol-type reaction. Reviewing the state of the art in heterogeneous catalysis in flow chemistry - a "hot topic" and rapidly developing area of organic synthesis - the book will provide readers with a deeper understanding of fine chemical flow synthesis and its future prospects.
| ISBN: | 9789811972607 |
| Publication date: | 2nd December 2023 |
| Author: | Yuki Saito |
| Publisher: | Springer an imprint of Springer Nature Singapore |
| Format: | Paperback |
| Pagination: | 172 pages |
| Series: | Springer Theses |
| Genres: |
Catalysis Organometallic chemistry Sustainability Industrial chemistry and chemical engineering Chemistry |
This book describes the development of two kinds of continuous-flow transformation using heterogeneous catalysts, and explains how they can be applied in the multistep synthesis of active pharmaceutical ingredients. It demonstrates and proves that fine chemicals can be synthesized under continuous-flow conditions using heterogeneous catalysis alone. Importantly, the book also proposes a general concept and strategy for achieving multistep flow synthesis and developing heterogeneous catalysts, and shows that commercially available anion exchange resin can be used as a water-tolerant strong base catalyst for various types of continuous-flow aldol-type reaction. Reviewing the state of the art in heterogeneous catalysis in flow chemistry - a "hot topic" and rapidly developing area of organic synthesis - the book will provide readers with a deeper understanding of fine chemical flow synthesis and its future prospects.
Multistep Continuous Flow Synthesis of Fine Chemicals With Heterogeneous Catalysts features in the following genres: Catalysis, Organometallic chemistry, Sustainability, Industrial chemistry and chemical engineering, Chemistry
Multistep Continuous Flow Synthesis of Fine Chemicals With Heterogeneous Catalysts is available in Paperback, Hardback
Multistep Continuous Flow Synthesis of Fine Chemicals With Heterogeneous Catalysts was written by Yuki Saito and published by Springer an imprint of Springer Nature Singapore
Multistep Continuous Flow Synthesis of Fine Chemicals With Heterogeneous Catalysts has 172 pages
Yes it is part of Springer Theses series
£161.99