In this thesis, the author outlines the discovery of an effect common to representative examples of all Li salt-free Wittig Reactions. The implications of such a universally applicable effect are that all such Wittig reactions occur through the same mechanism. Although the Wittig reaction was first discovered in 1953, its reaction mechanism has never been definitively settled with many different variants proposed and disproved. The work in this thesis shows conclusively that for [2+2] cycloadditions all Wittig reactions occur by the same irreversible mechanism. In addition, the author also describes a new chromatography-free method for the removal of phosphine oxide from the alkene crude product of the Wittig reaction. The work in this thesis has led to several publications in high-profile journals.
| ISBN: | 9783642320446 |
| Publication date: | 7th February 2013 |
| Author: | Peter A Byren |
| Publisher: | Springer an imprint of Springer Berlin Heidelberg |
| Format: | Hardback |
| Pagination: | 314 pages |
| Series: | Springer Theses |
| Genres: |
Organic chemistry Quantum and theoretical chemistry Analytical chemistry |
In this thesis, the author outlines the discovery of an effect common to representative examples of all Li salt-free Wittig Reactions. The implications of such a universally applicable effect are that all such Wittig reactions occur through the same mechanism. Although the Wittig reaction was first discovered in 1953, its reaction mechanism has never been definitively settled with many different variants proposed and disproved. The work in this thesis shows conclusively that for [2+2] cycloadditions all Wittig reactions occur by the same irreversible mechanism. In addition, the author also describes a new chromatography-free method for the removal of phosphine oxide from the alkene crude product of the Wittig reaction. The work in this thesis has led to several publications in high-profile journals.
Investigation of Reactions Involving Pentacoordinate Intermediates features in the following genres: Organic chemistry, Quantum and theoretical chemistry, Analytical chemistry
Investigation of Reactions Involving Pentacoordinate Intermediates is available in Hardback
Investigation of Reactions Involving Pentacoordinate Intermediates was written by Peter A Byren and published by Springer an imprint of Springer Berlin Heidelberg
Investigation of Reactions Involving Pentacoordinate Intermediates has 314 pages
Yes it is part of Springer Theses series