As part of a collaboration between two different groups in chemistry and biochemistry, Thom Sharp presents here his thesis work on the development of new methods for cryoelectron microscopy. Throughout his Ph.D., Thom had to master a whole range of techniques including modelling, molecular biology and microscopy. Using these skills to tackle an outstanding problem, the pursuit of high-resolution structures of peptide-based materials, Thom highlights in this thesis his newly developed methods for analysing and processing this particular type of electron microscopy data. This thesis gives the first molecular description of a de-novo designed peptide-based material. In general, this research will have a huge impact on the peptide assembly field, and also in electron microscopy as it introduces new methods and approaches, all of which are Thom's inventions and are described in this thesis.
| ISBN: | 9783319350233 |
| Publication date: | 23rd August 2016 |
| Author: | Thomas H Sharp |
| Publisher: | Springer an imprint of Springer International Publishing |
| Format: | Paperback |
| Pagination: | 150 pages |
| Series: | Springer Theses |
| Genres: |
Analytical chemistry Engineering applications of bio-materials Biophysics |
As part of a collaboration between two different groups in chemistry and biochemistry, Thom Sharp presents here his thesis work on the development of new methods for cryoelectron microscopy. Throughout his Ph.D., Thom had to master a whole range of techniques including modelling, molecular biology and microscopy. Using these skills to tackle an outstanding problem, the pursuit of high-resolution structures of peptide-based materials, Thom highlights in this thesis his newly developed methods for analysing and processing this particular type of electron microscopy data. This thesis gives the first molecular description of a de-novo designed peptide-based material. In general, this research will have a huge impact on the peptide assembly field, and also in electron microscopy as it introduces new methods and approaches, all of which are Thom's inventions and are described in this thesis.
Biomolecular Imaging at High Spatial and Temporal Resolution in Vitro and in Vivo features in the following genres: Analytical chemistry, Engineering applications of bio-materials, Biophysics
Biomolecular Imaging at High Spatial and Temporal Resolution in Vitro and in Vivo is available in Paperback, Hardback
Biomolecular Imaging at High Spatial and Temporal Resolution in Vitro and in Vivo was written by Thomas H Sharp and published by Springer an imprint of Springer International Publishing
Biomolecular Imaging at High Spatial and Temporal Resolution in Vitro and in Vivo has 150 pages
Yes it is part of Springer Theses series