The union of covalent and noncovalent chemistries manifested in the mechanical bond represents one of the great chemical triumphs of the last half century. However, until recently, the preparation of mechanically interlocked compounds has often been an inefficient and limiting process. This thesis provides a detailed account of the great strides taken to increase the synthetic accessibility of donor-acceptor mechanically interlocked molecules by the application of highly efficient and ultra mild chemical transformations during their template-directed synthesis. These new departures in synthesis have indeed played a transformative role in that more complex, higher-order, and functional architectures - once only a dream - are now comfortably within reach. Specifically, the formation of mechanical bonds in higher order rotaxanes and catenanes has become ever easier through the use of highly efficient click chemistries. The resulting mechanically interlocked compounds are functional molecular media for a host of applications including information storage, mechanical actuation, and drug release.
| ISBN: | 9781441996466 |
| Publication date: | 14th June 2011 |
| Author: | Jason M Spruell |
| Publisher: | Springer an imprint of Springer New York |
| Format: | Hardback |
| Pagination: | 119 pages |
| Series: | Springer Theses |
| Genres: |
Catalysis Nanotechnology Nanosciences |
The union of covalent and noncovalent chemistries manifested in the mechanical bond represents one of the great chemical triumphs of the last half century. However, until recently, the preparation of mechanically interlocked compounds has often been an inefficient and limiting process. This thesis provides a detailed account of the great strides taken to increase the synthetic accessibility of donor-acceptor mechanically interlocked molecules by the application of highly efficient and ultra mild chemical transformations during their template-directed synthesis. These new departures in synthesis have indeed played a transformative role in that more complex, higher-order, and functional architectures - once only a dream - are now comfortably within reach. Specifically, the formation of mechanical bonds in higher order rotaxanes and catenanes has become ever easier through the use of highly efficient click chemistries. The resulting mechanically interlocked compounds are functional molecular media for a host of applications including information storage, mechanical actuation, and drug release.
The Power of Click Chemistry for Molecular Machines and Surface Patterning features in the following genres: Catalysis, Nanotechnology, Nanosciences
The Power of Click Chemistry for Molecular Machines and Surface Patterning is available in Hardback
The Power of Click Chemistry for Molecular Machines and Surface Patterning was written by Jason M Spruell and published by Springer an imprint of Springer New York
The Power of Click Chemistry for Molecular Machines and Surface Patterning has 119 pages
Yes it is part of Springer Theses series