Radiosensitizers and Radiochemotherapy in the Treatment of Cancer catalogs and describes the mechanism of action for entities characterized as radiosensitizers. Developments in the biological and physical sciences have introduced new radiosensitizers and defined novel targets for radiosensitization. As a result, a book about radiosensitization must now address a huge range of topics, covering everything from molecular oxygen and high Z elements to monoclonal antibodies and complex phytochemicals. At the molecular level, the understanding of the molecular consequences of DNA damage and the DNA damage response have informed the development of targeted radiosensitizers and shed light on the mode of action of radiochemotherapy protocols of known clinical efficacy. In this book the mechanisms of action at the molecular and cellular level are described for documented radiosensitizers including, where applicable, a brief history of their clinical use and most recent clinical results. In addition, the clinical context is addressed including the importance of factors such as dose and dose rate, normal tissue toxicity, and drug delivery. Intuitively organized by topic and application, the book includes extensive illustrations, end-of-chapter summaries, and a wealth of references.
| ISBN: | 9780367378028 |
| Publication date: | 19th September 2019 |
| Author: | Shirley Montreal General HospitalMcGill University, Canada Lehnert |
| Publisher: | CRC Press an imprint of Taylor & Francis Ltd |
| Format: | Paperback |
| Pagination: | 548 pages |
| Series: | Series in Medical Physics and Biomedical Engineering |
| Genres: |
Oncology Pharmacology Medical physics |
Radiosensitizers and Radiochemotherapy in the Treatment of Cancer catalogs and describes the mechanism of action for entities characterized as radiosensitizers. Developments in the biological and physical sciences have introduced new radiosensitizers and defined novel targets for radiosensitization. As a result, a book about radiosensitization must now address a huge range of topics, covering everything from molecular oxygen and high Z elements to monoclonal antibodies and complex phytochemicals. At the molecular level, the understanding of the molecular consequences of DNA damage and the DNA damage response have informed the development of targeted radiosensitizers and shed light on the mode of action of radiochemotherapy protocols of known clinical efficacy. In this book the mechanisms of action at the molecular and cellular level are described for documented radiosensitizers including, where applicable, a brief history of their clinical use and most recent clinical results. In addition, the clinical context is addressed including the importance of factors such as dose and dose rate, normal tissue toxicity, and drug delivery. Intuitively organized by topic and application, the book includes extensive illustrations, end-of-chapter summaries, and a wealth of references.
Radiosensitizers and Radiochemotherapy in the Treatment of Cancer features in the following genres: Oncology, Pharmacology, Medical physics
Radiosensitizers and Radiochemotherapy in the Treatment of Cancer is available in Paperback
Radiosensitizers and Radiochemotherapy in the Treatment of Cancer was written by Shirley Montreal General HospitalMcGill University, Canada Lehnert and published by CRC Press an imprint of Taylor & Francis Ltd
Radiosensitizers and Radiochemotherapy in the Treatment of Cancer has 548 pages
Yes it is part of Series in Medical Physics and Biomedical Engineering series
£63.89