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p53: The Gene that Cracked the Cancer Code
"Bloomsbury presents P53: The Gene that cracked the cancer code by Sue Armstrong, read by Stephanie Beattie The BMA Medical Book Award-shortlisted story of the search for p53 - the most important gene in medicine. All of us have lurking in our DNA a most remarkable gene, which has a crucial job – it protects us from cancer. Known simply as p53, this gene constantly scans our cells to ensure that they grow and divide without mishap. If a cell makes a mistake in copying its DNA during the process of division, p53 stops it in its tracks, summoning a repair team before allowing the cell to carry on dividing. If the mistake is irreparable and the rogue cell threatens to grow out of control, p53 commands the cell to commit suicide. Cancer cannot develop unless p53 itself is damaged or prevented from functioning normally. This book tells the story of medical science’s mission to unravel the mysteries of this crucial gene, and to get to the heart of what happens in our cells when they turn cancerous, highlighting the tremendous recent advances made in our understanding of cancer. P 2026 Bloomsbury Publishing PLC C 2014 Sue Armstrong"
Sue Armstrong (Author), Stephanie Beattie (Narrator)
Audiobook
"As DCI Matilda Darke unravels a chilling cold case, she discovers some truths are deadly – and someone will stop at nothing to keep the past buried… ‘Matilda Darke is the perfect heroine’ Elly Griffiths RUNNING FROM HER PAST Leaving behind Sheffield, her friends and her job, a grieving DCI Matilda Darke finds solace in the wild, untamed beauty of the Lake District. But she can’t outrun her reputation. A COLD CASE PC Alison Pemberton is living in the shadow of her twin sisters, who were abducted thirty years ago. As the only witness, Alison has spent her life trying to remember the details of that fateful summer day and discover the truth about what happened to her sisters and why, a few months later, her father also disappeared. A TRUTH THAT SHOULD HAVE STAYED BURIED Matilda finds herself agreeing to try and unearth the truth about the Pemberton twins. With nothing left to lose, Matilda throws herself into the cold case, but someone doesn’t want her digging up the past and will do anything to keep the truth hidden… Praise for Michael Wood ‘A master of horror and suspense’ ⭐⭐⭐⭐⭐ 'One of the best books ever, in one of the best series ever! It is THAT good!’ ⭐⭐⭐⭐⭐ ‘Wow what a book… I adore this series and every book is better and better’ ⭐⭐⭐⭐⭐ ‘This book sets off at a hundred miles an hour and never lets off… this is my favourite detective series’ ⭐⭐⭐⭐⭐ ‘Exciting, tense and compelling… shocking and brilliant’ ⭐⭐⭐⭐⭐ ‘Wow! Wow! Wow! The twists keep on coming to the last page’ ⭐⭐⭐⭐⭐ ‘I don’t have words! Wow just wow! This blew me away. DCI Matilda Darke and her team are my favourite detectives’ ⭐⭐⭐⭐⭐ ‘This book had a bit of everything… some crazy twists and turns’ ⭐⭐⭐⭐⭐ ‘Another cracking, nail-biting read’ ⭐⭐⭐⭐⭐"
Michael Wood (Author), Stephanie Beattie (Narrator)
Audiobook
"DCI Matilda Darke is back. And it might be her most personal case yet. ‘Matilda Darke is the perfect heroine’ Elly Griffiths FIVE PERFECT MURDERS DCI Matilda Darke receives an anonymous email from someone claiming to have committed the perfect murder. Experience tells her this isn’t possible, but as she investigates, she discovers a killer questioning everything she’s ever known. HIDDEN IN PLAIN SIGHT Now, Matilda is on the trail of a murderer who targets the most vulnerable people in society. Apart from ‘With Sympathy…’ cards, hand delivered to the family of his victims, he leaves no trace of his crimes. A KILLER’S DEADLY GAME As the threat escalates, and those closest to Matilda are targeted, she finds herself isolated and alone in bringing down her opponent before it’s game over. After all, there can only be one winner in this game of cat-and-mouse, and the clock is ticking… Praise for Michael Wood ‘A master of horror and suspense’ 'One of the best books ever, in one of the best series ever! It is THAT good!’ ‘Wow what a book… I adore this series and every book is better and better’ ‘This book sets off at a hundred miles an hour and never lets off… this is my favourite detective series’ ‘Exciting, tense and compelling… shocking and brilliant’ ‘Wow! Wow! Wow! The twists keep on coming to the last page’ ‘I don’t have words! Wow just wow! This blew me away. DCI Matilda Darke and her team are my favourite detectives’ ‘This book had a bit of everything… some crazy twists and turns’ ‘Another cracking, nail-biting read’"
Michael Wood (Author), Stephanie Beattie (Narrator)
Audiobook
"Rosalind Stopps is a born storyteller with a gift of balancing the gritty and dark with humour … a blooming marvellous page turner' Reader review ‘Warm, wise and compelling’ Daily Mail 'This story is fantastic' Reader review ‘A heart-warming tale of courage and friendship’ The Sun 'An outstanding read' Reader review ‘This standout read is both dark and uplifting’ Fabulous * * * Ever since her beloved Jed died, all Virginia wants is to be left alone. But the little girl who lives down the street is so sweet, that even in her grief-fuelled state Virginia’s heart softens whenever she sees her. And that’s why Virginia knows there’s something wrong in the little girl’s house. So when the mother asks Virginia to take her child far away, somewhere safe, Virginia says yes. The last thing Virginia would call herself is a hero. She’s just doing what anyone else would do, right? But when she realises how much danger the child is in, she knows she needs to do everything she can to keep her safe … Because sometimes it’s the most ordinary people who do the most extraordinary things. * * * Perfect for fans of Jennie Godfrey, Rachel Joyce and Liz Nugent."
Rosalind Stopps (Author), Stephanie Beattie (Narrator)
Audiobook
"Preorder the BRAND NEW psychological thriller from #1 bestseller Rona Halsall He killed my husband. Now I've promised to be his wife. After my first husband died, I thought my heart was completely broken, and that I'd never feel happy again. Until I met Theo. He's a doctor. A man who seems good and caring and kind. Soon after we start dating, he says he wants to marry me. And even though his grown-up children are less sure about me, to everyone else it's the second chance for love and happiness I deserve. But the truth is maybe his children are right to be suspicious. Because I know something about Theo. That he was there in the operating theatre the day my first husband died. And I think it was his fault. Am I in exactly the right place for revenge? Or am I living with a killer? A pulse-pounding cat-and-mouse psychological thriller, full of the most jaw-dropping twists and turns. Perfect for fans of K. L. Slater, Lisa Jewell and Freida McFadden Bestselling authors are loving The Fiancé: 'Wow. Wow. Wow. A fantastic read. Just my sort of thriller. Twisty, moved along apace, and I was desperate to see how it would play out. Strongly recommend this amazing book. Readers will not be disappointed. ' Diana Wilkinson 'A thrillingly twisty rollercoaster of a read!' Valerie Keogh 'OMG THIS BOOK!!! What a rollercoaster of a read! From the very first page. . . I was drawn into Anna's story and couldn't wait to get to the heart-pounding ending. A masterful and twisty tale. I literally had no idea who to trust and who to fear until the very end - I was suspicious of everyone. Just my kind of book! A psychological thriller that'll keep you up late - guaranteed!' Samantha Hayes 'Unputdownable. . . literally. I knew I shouldn't have started it because that was my afternoon gone! A really gripping read, I couldn't turn the pages fast enough and now my brain is scrambled. Cunningly clever and the twists just keep rolling. ' Karen King 'A gripping, fast-paced thriller that ramps up the tension with every chapter. Halsall's portrayal of a grieving widow is so flawless you can't help but root for Anna, even if her intentions are morally questionable. The result is a twisted game of cat and mouse in which everyone has something to hide. Shut your door and turn off your phone - you won't want to put this book down until you've reached the end!' AJ McDine 'Wow - what a totally gripping thriller. I was on the edge of my seat! Rona's best yet, and one of the best thrillers of the year. ' Ruby Speechley 'Twists and turns aplenty! Psychological thriller fans will definitely not be disappointed!' L. H. Stacey Readers are completely gripped too! 'WOW WOW WOW I absolutely loved this book. . . The characters are brilliant and the twists you would never have guessed. . . Can't wait for her next one!' Netgalley reviewer ⭐⭐⭐⭐⭐ 'Wow. . . Somany twists and turns that made me devour this book in one sitting! Wow, what can I say - what an ending - really wasn't expecting it! I'd really recommend this book, you won't regret it!' Netgalley reviewer ⭐⭐⭐⭐⭐ 'One of those books where you need to make sure your free for a few hours cause once you start you won't be able to put it down. . . I loved the many twists and turns throughout and WOW the ending was amazing. . . A fantastic thriller. ' Netgalley reviewer ⭐⭐⭐⭐⭐ 'A story of revenge as a dish best served cold. . . Tense, dark, exciting. . . Kept me reading non-stop. ' Netgalley reviewer ⭐⭐⭐⭐⭐"
Rona Halsall (Author), Stephanie Beattie (Narrator)
Audiobook
"Preorder the first in a new series from bestselling author, Julie Houston!'Warm and poignant, brimming with heart and humour and filled with characters I was rooting for. Loved this class act!' Fiona Gibson Robyn Allen is finally getting closer to her dream of West End stardom. And along with her role dancing in the latest hot musical, she's being wined and dined by an equally hot man - the wildly successful and well-connected Fabian Carrington. But one slip up and her dreams are shattered, and Robyn has to hobble back to the Yorkshire village of Beddingfield, and the life she hoped she'd escaped. Moving back into her mum's house with her recalcitrant teenage sister Sorrel, next door to her older sister Jess who's fed up with picking up the slack, is not how Robyn pictured her year. But there's more to come. Sorrel needs a new school, and the school needs a new drama teacher. Despite having vowed never to teach again, Robyn knows she has to support her sister. So together Sorrel and Robyn vow to take on St Mede's - home to jokers, tearaways and trouble-makers, but with a hidden heartbeat ready to be inspired. And who knows, the kids might have something to teach Robyn about life too. . . Welcome to the village of Beddingfield and the first book in bestseller Julie Houston's new series set in Yorkshire. Funny, fabulous, heart-warming and hilarious, you'll never forget the Allen sisters and their one-of-a-kind community. Perfect for fans of Jo Bartlett, Cathy Bramley and Philippa Ashley. 'There is too much to love about Julie's latest book. This story of three sisters is funny, heart-warming and will keep you hooked to the final page. ' Carmen ReidPraise for Julie Houston:'This is a gorgeous, warm-hearted read with a cast of characters that you can't help but root for. It's a beautiful depiction of the special bond between sisters - warts and all and I can't wait to see where we go next with the Allen family. ' Freya Kennedy'Warm, funny and well written, with a page-turning plot, this book has everything! I loved it!' Katie Fforde'Julie Houston at her best - heartfelt and hilarious' Sandy Barker'Laugh-out-loud hilarious and heartwarming!' Mandy Baggot'A tour de force of beautiful, funny and emotional storytelling' Fay Keenan'A warm, funny story of sisters and the secrets they keep' Sheila O'Flanagan'This book is an absolute gigglefest with characters you'll fall in love with!' Katie GingerReaders love Julie Houston:'Julie Houston knows how to pluck the readers' heartstrings . If ever anyone feels down, Julie's books should be available on prescription. . . the perfect pick-me-up. ''If you are looking to indulge in a tale of Yorkshire and its fabulously feisty, independent women, then Julie's latest offering should be your first choice. Packed with hopeless romanticism, witty banter and a satisfying ending, this is a splendid read which I heartily recommend. ''This was just what I needed to restart the reading bug and has left me wanting to get stuck into all of the books again, fab characters, great storylines and lots of 'Will they, won't they' situations. I buddy read this with a friend but we both ended up binge reading as you find yourself getting lost in the book and wanting to know what's going to happen next. . I would easily recommend Julie to anyone looking for something to get them out of a book slump or just who wants a good book to get lost in!''I love all of Julie Houston's novels and this one is a cracker. Great characters, a lovely setting and a very entertaining and gripping read. Highly recommended. Don't go on holiday without it!!'"
Julie Houston (Author), Stephanie Beattie (Narrator)
Audiobook
"'One of the best books ever, in one of the best series ever! It is THAT good!’ NetGalley Reviewer ‘A master of horror and suspense’ NetGalley Reviewer ‘Matilda Darke is the perfect heroine’ Elly Griffiths A MISSING DETECTIVE DCI Matilda Darke has been kidnapped and her nemesis, Steve Harrison appears to be behind it. He’s currently residing in the supermax of Wakefield Prison and spends twenty-three hours a day in his cell, so how could he possibly be responsible? A SERIAL KILLER WITH A VENGEANCE As Matilda’s team race to find her, they’re alerted to a body found in an abandoned car on the outskirts of Sheffield. With forensics scouring the woodland for clues, the last thing they expect is for the body count to rise. A RACE AGAINST TIME Meanwhile the search intensifies for the DCI when a video of her kidnapping is leaked to the media. And as she desperately tries to uncover what has led to her being held captive in an underground cell, she’s about to find out how much danger she’s truly in. If Matilda’s team don’t find her soon, they might not find her at all… Early readers have been blown away by Below Ground: ‘Wow what a book… I adore this series and every book is better and better’ ‘This book sets off at a hundred miles an hour and never lets off… this is my favourite detective series’ ‘Exciting, tense and compelling… shocking and brilliant’ ‘Wow! Wow! Wow! The twists keep on coming to the last page’ ‘I don’t have words! Wow just wow! This blew me away. DCI Matilda Darke and her team are my favourite detectives’ ‘This book had a bit of everything… some crazy twists and turns’ ‘Another cracking, nail-biting read’"
Michael Wood (Author), Stephanie Beattie (Narrator)
Audiobook
"He took her voice She took it back Don’t miss the next nerve-shredding instalment in the DCI Matilda Darke Thriller series… A CENSURED DETECTIVE WITH NO LEADS DCI Matilda Darke and her team have been restricted under special measures after a series of calamitous scandals nearly brought down the South Yorkshire police force. A BRUTAL ATTACK WITH NO WITNESSES Now Matilda is on the trail of another murderer, an expert in avoiding detection with no obvious motive but one obvious method. A DEPRAVED KILLER WHO LEAVES NO TRACES When his latest victim survives the attack despite her vocal cords being severed, Matilda is more convinced than ever of the guilt of her key suspect. If only she had a way to prove it… Silent Victim is an unputdownable crime thriller with twists that will make your jaw drop – perfect for fans of Kathy Reichs and Ann Cleeves. Praise for the DCI Matilda Darke Series: ‘Tense, twisty, emotional and gripping. Will definitely be reading more from Matilda Darke and this gets a huge 5 stars from me!’ Angela Marsons ‘Matilda Darke is an excellent character’ BA Paris ‘This explosive novel is already making a bang – with reviewers comparing Michael’s work to that of his heroes Val McDermid and James Oswald’ Sheffield Star ‘DCI Matilda Darke is going places’ James Oswald ‘Crackling dialogue, dark wit and an exciting ending. Recommended if you liked Happy Valley’ Mark Edwards ‘Budge up Jed Mercurio … when you are done working on Line of Duty I think it is time for you to meet Matilda’ LJ, Read and Rated Book Review Blog ‘Excellent plotting. The twists keep on coming making this an irresistible read’ Michael J. Malone ‘I really enjoyed getting to know DCI Matilda Darke’ Robert Bryndza ‘DCI Matilda Darke is the perfect heroine’ Elly Griffiths"
Michael Wood (Author), Stephanie Beattie (Narrator)
Audiobook
"A must-read for fans of Kate Quinn and Kristin Hannah! Paris 1930s A promise that binds them together. A war that pulls them apart. Childhood companions Fleur and Colette make a vow, under the trailing ivy of their secret garden, that they will be secret sisters forever. But as they grow up, the promises of childhood are put to the ultimate test. For Colette is the daughter of the house, and her life is all jazz clubs, silk dresses and chilled champagne, while Fleur is the orphan niece of the housekeeper and doesn’t feel like she belongs anywhere. Years later, in 1939, life as they know it will never be the same. As the German tanks roll in and Paris becomes an occupied city, the promise they made as children will have consequences they could never have imagined… Readers love Daughters of Paris: ‘I’m an avid reader of WWII novels and this was up there with the best…Strong women, enduring friendship and love’ Bev ‘Has it all: mystery, suspense, history, strong female characters, and kept me engaged throughout…excellent’ Rachel ‘Outstanding…five stars from me’ Karren ‘It's been a while since I cried at a book!’ Shanon ‘I really enjoyed this story of loyalty, love, bravery and true friendship…a very thought-provoking read’ Chrissie ‘This was a lovely WWII historical fiction novel that focused on the relationships between the female characters, which I appreciated. And there is romance, of course, because what is a wartime novel set in Paris without a bit of romance?’ Lorin"
Elisabeth Hobbes (Author), Stephanie Beattie (Narrator)
Audiobook
"Matilda Darke is back… APRIL 2020: LOCKDOWN DI Brady has been tracing victims of systemic abuse at a local children’s home after a high-profile accusation pitched it into the spotlight – a case that couldn’t be more personal. As Matilda and her team piece together the disturbing picture of the history of the home, it soon becomes clear that this is much bigger than they ever suspected. But nothing prepares them for what they uncover next… The Lost Children is an utterly gripping crime thriller weaving a breakneck tale of a vast network of secrets and lies, a relentless detective determined to sabotage it, and a murder that shatters two decades of silence. Praise for the DCI Matilda Darke Series: ‘Tense, twisty, emotional and gripping. Will definitely be reading more from Matilda Darke and this gets a huge 5 stars from me!’ Angela Marsons ‘Matilda Darke is an excellent character’ BA Paris ‘This explosive novel is already making a bang – with reviewers comparing Michael’s work to that of his heroes Val McDermid and James Oswald’ Sheffield Star ‘DCI Matilda Darke is going places’ James Oswald ‘Crackling dialogue, dark wit and an exciting ending. Recommended if you liked Happy Valley’ Mark Edwards ‘Budge up Jed Mercurio … when you are done working on Line of Duty I think it is time for you to meet Matilda’ LJ, Read and Rated Book Review Blog ‘Excellent plotting. The twists keep on coming making this an irresistible read’ Michael J. Malone ‘I really enjoyed getting to know DCI Matilda Darke’ Robert Bryndza ‘DCI Matilda Darke is the perfect heroine’ Elly Griffiths"
Michael Wood (Author), Stephanie Beattie (Narrator)
Audiobook
"‘Tense, twisty, emotional and gripping. Will definitely be reading more from Matilda Darke and this gets a huge 5 stars from me!’ Angela Marsons ‘Matilda Darke is an excellent character’ BA Paris A TEAM TORN APART Nine months ago DCI Matilda Darke survived a bullet to the head. The brutal attack claimed dozens of lives, including those she loved most, and the nightmares still plague her every waking thought. A MEMORY SHE’D RATHER FORGET Now, she’s ready to get back on the job. But a new terror awaits. A woman is found murdered and her wounds look eerily similar to several cold cases. Desperate to find a lead, DCI Darke and her team must face a terrifying truth: a serial killer is on the loose in Sheffield. A THREAT CLOSE TO HOME Matilda has led countless murder investigations before but the lingering emotional scars from her ordeal and the uneasiness within her once-tight team have left tensions high. As the body count rises, Matilda realises that this might just be where it all ends. The brand new instalment in the DCI Matilda Darke series will leave you on the edge of your seat. Perfect for fans of Angela Marsons, Kathy Reichs and Peter James. ‘Had me in tears at one point. Brilliant, non-stop stuff. Feel like I’ve been through some sort of psychological bombardment. Exhausted. Terrific’ John Barlow, author of Right to Kill"
Michael Wood (Author), Stephanie Beattie (Narrator)
Audiobook
"Your life is in his hands. In the gripping new serial killer thriller from Michael Wood, Matilda Darke faces a vicious killer pursuing his own brand of lethal justice. Perfect for fans of Angela Marsons and Helen Fields. There’s a killer in your house. The Hangman waits in the darkness. He knows your darkest secrets. He’ll make you pay for all the crimes you have tried desperately to forget. And he is closer than you think. DCI Matilda Darke is running out of time. Fear is spreading throughout the city. As the body count rises, Matilda is targeted and her most trusted colleagues fall under suspicion. But can she keep those closest to her from harm? Or is it already too late?"
Michael Wood (Author), Stephanie Beattie (Narrator)
Audiobook
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