Adi Haber's thesis summarises the use of a new entity, the corrole, to combat one of the major cardiovascular diseases, atherosclerosis. She examines the effects of three rationally designed corrole-metal complexes on some of the many variables which contribute to the development of atherosclerosis. There is a focus on both the "bad" and "good" cholesterol carriers, LDL and HDL. Adi Haber proceeds from basic findings in pure chemistry through biochemical and cell culture tests to in vivo examinations. The work in this thesis shows that corroles are highly efficient both for early and late treatment of atherosclerosis in animals. These results will pave the way for ongoing regulated preclinical studies focussed on the development of metallocorroles as potential drugs for treating cardiovascular diseases.
| ISBN: | 9783642442506 |
| Publication date: | 11th June 2014 |
| Author: | Adi Haber |
| Publisher: | Springer an imprint of Springer Berlin Heidelberg |
| Format: | Paperback |
| Pagination: | 88 pages |
| Series: | Springer Theses |
| Genres: |
Organometallic chemistry Medical research Biochemistry |
Adi Haber's thesis summarises the use of a new entity, the corrole, to combat one of the major cardiovascular diseases, atherosclerosis. She examines the effects of three rationally designed corrole-metal complexes on some of the many variables which contribute to the development of atherosclerosis. There is a focus on both the "bad" and "good" cholesterol carriers, LDL and HDL. Adi Haber proceeds from basic findings in pure chemistry through biochemical and cell culture tests to in vivo examinations. The work in this thesis shows that corroles are highly efficient both for early and late treatment of atherosclerosis in animals. These results will pave the way for ongoing regulated preclinical studies focussed on the development of metallocorroles as potential drugs for treating cardiovascular diseases.
Metallocorroles for Attenuation of Atherosclerosis features in the following genres: Organometallic chemistry, Medical research, Biochemistry
Metallocorroles for Attenuation of Atherosclerosis is available in Paperback, Hardback
Metallocorroles for Attenuation of Atherosclerosis was written by Adi Haber and published by Springer an imprint of Springer Berlin Heidelberg
Metallocorroles for Attenuation of Atherosclerosis has 88 pages
Yes it is part of Springer Theses series