Jason Woolford's thesis describes for the first time, a double [3+2] photocycloaddition of alkenes onto aromatic rings. Modern synthetic chemistry relies on the ability of researchers to uncover new and more efficient ways of creating highly complex structures. This work describes a novel, environmentally friendly photochemical step that converts in one pot, trivial starting materials into otherwise difficult to construct fenstrane frameworks. The rigid cores of these frameworks have significant potential in drug design. Moreover, the novelty of this work overtakes many other methods for the creation of chiral centres. No less than seven chiral centres are created in the photochemical step together with the formation of four carbon-carbon bonds and multifused rings. Jason's innovative work has been the subject of several publications in peer-reviewed journals.
| ISBN: | 9783642270437 |
| Publication date: | 27th November 2013 |
| Author: | Jason A Woolford |
| Publisher: | Springer an imprint of Springer Berlin Heidelberg |
| Format: | Paperback |
| Pagination: | 184 pages |
| Series: | Springer Theses |
| Genres: |
Organic chemistry Medicinal chemistry Analytical chemistry |
Jason Woolford's thesis describes for the first time, a double [3+2] photocycloaddition of alkenes onto aromatic rings. Modern synthetic chemistry relies on the ability of researchers to uncover new and more efficient ways of creating highly complex structures. This work describes a novel, environmentally friendly photochemical step that converts in one pot, trivial starting materials into otherwise difficult to construct fenstrane frameworks. The rigid cores of these frameworks have significant potential in drug design. Moreover, the novelty of this work overtakes many other methods for the creation of chiral centres. No less than seven chiral centres are created in the photochemical step together with the formation of four carbon-carbon bonds and multifused rings. Jason's innovative work has been the subject of several publications in peer-reviewed journals.
The Double [3+2] Photocycloaddition Reaction features in the following genres: Organic chemistry, Medicinal chemistry, Analytical chemistry
The Double [3+2] Photocycloaddition Reaction is available in Paperback, Hardback
The Double [3+2] Photocycloaddition Reaction was written by Jason A Woolford and published by Springer an imprint of Springer Berlin Heidelberg
The Double [3+2] Photocycloaddition Reaction has 184 pages
Yes it is part of Springer Theses series