This thesis uses a systems-level approach to study the cellular metabolism, unveiling new mechanisms and responses that were impossible to reach with traditional reductionists procedures.
The results reported here have a potential application in areas like metabolic engineering and disease treatment. They could also be used in determining the accuracy of the gene essentiality of new genome-scale reconstructions.
Different methods and techniques, within the contexts of Systems Biology and the field known as Complex Networks Analysis have been applied in this work to show different features of the robustness of metabolic networks. The specific issues addressed here range from pure topological aspec
ts of the networks themselves to the balance of biochemical fluxes.
| ISBN: | 9783319876955 |
| Publication date: | 11th August 2018 |
| Author: | Oriol Güell |
| Publisher: | Springer an imprint of Springer International Publishing |
| Format: | Paperback |
| Pagination: | 151 pages |
| Series: | Springer Theses |
| Genres: |
Biotechnology Computational biology / bioinformatics Physical chemistry |
This thesis uses a systems-level approach to study the cellular metabolism, unveiling new mechanisms and responses that were impossible to reach with traditional reductionists procedures.
The results reported here have a potential application in areas like metabolic engineering and disease treatment. They could also be used in determining the accuracy of the gene essentiality of new genome-scale reconstructions.
Different methods and techniques, within the contexts of Systems Biology and the field known as Complex Networks Analysis have been applied in this work to show different features of the robustness of metabolic networks. The specific issues addressed here range from pure topological aspec
ts of the networks themselves to the balance of biochemical fluxes.
A Network-Based Approach to Cell Metabolism features in the following genres: Biotechnology, Computational biology / bioinformatics, Physical chemistry
A Network-Based Approach to Cell Metabolism is available in Paperback, Hardback
A Network-Based Approach to Cell Metabolism was written by Oriol Güell and published by Springer an imprint of Springer International Publishing
A Network-Based Approach to Cell Metabolism has 151 pages
Yes it is part of Springer Theses series
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