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HDAC/HAT Function Assessment and Inhibitor Development

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HDAC/HAT Function Assessment and Inhibitor Development Synopsis

This detailed collection covers how the biological functions of histone deacetylases (HDACs) and histone acetyltransferases (HATs) can be detected in various experimental settings, both in vivo and in vitro. The book also covers the generation and specificity of deacetylase inhibitors and how such agents can be used to test experimental hypotheses. Written for the popular Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, as well as tips on troubleshooting and avoiding known pitfalls.


Comprehensive and practical, HDAC/HAT Function Assessment and Inhibitor Development: Methods and Protocols serves as an ideal guide to this vital area of study.

About This Edition

ISBN: 9781493965250
Publication date:
Author: Springer Science+Business Media
Publisher: Humana Press an imprint of Springer New York
Format: Hardback
Pagination: 415 pages
Series: Methods in Molecular Biology
Genres: Biochemistry

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