It is increasingly recognized that various transporter proteins are expressed throughout the body and determine absorption, tissue distribution, biliary and renal elimination of endogenous compounds and drugs and drug effects. This book will give an overview on the transporter families which are most important for drug therapy. Most chapters will focus on one transporter family highlighting tissue expression, substrates, inhibitors, knock-out mouse models and clinical studies.
| ISBN: | 9783642266454 |
| Publication date: | 25th February 2013 |
| Author: | Martin F Fromm, Richard B Kim |
| Publisher: | Springer an imprint of Springer Berlin Heidelberg |
| Format: | Paperback |
| Pagination: | 454 pages |
| Series: | Handbook of Experimental Pharmacology |
| Genres: |
Pharmacology Medical microbiology and virology Renal medicine and nephrology Physiology Medicinal chemistry Clinical and internal medicine |