First published in 1986: This two-volume set provides essential information on the general princi-ples of target organ toxicity. Pharmacokinetics, metabolic activation and key defense mechanisms, excretion, species variation, and tissue-specific biochemistry are explored comprehensively. These general principles are then illustrated using specific examples of toxicity to different target organs and systems. DNA modifi-cation and repair in tumor induction, and specificity in tumor initiation are also examined. Of primary interest to toxicologist, pharma-cologists, biochemists, and environmental toxicologists.
ISBN: | 9780367258719 |
Publication date: | 30th June 2020 |
Author: | Gerald M Cohen |
Publisher: | CRC Press an imprint of Taylor & Francis Ltd |
Format: | Hardback |
Pagination: | 234 pages |
Series: | Routledge Revivals |
Genres: |
Biochemistry |