Jason X.-J. Yuan, MD, PhD is Professor of Medicine, University of Illinois at Chicago, Chicago, IL Joe G.N. Garcia, MD is Earl Banes Professor of Medicine and Vice Chancellor for Research, University of Illinois at Chicago, Chicago, IL Charles A. Hales, MD is Professor of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA Stuart Rich, MD is Professor of Medicine, University of Chicago, Chicago, IL Stephen L. Archer, MD is Harold Hines Jr. Professor of Medicine and Chief of Cardiology, University of Chicago, Chicago, IL John B. West, MD, PhD, DSc is Distinguished Professor of Physiology and Medicine, University of California, San Diego, La Jolla, CA