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See below for a selection of the latest books from Toxicology (non-medical) category. Presented with a red border are the Toxicology (non-medical) books that have been lovingly read and reviewed by the experts at Lovereading. With expert reading recommendations made by people with a passion for books and some unique features Lovereading will help you find great Toxicology (non-medical) books and those from many more genres to read that will keep you inspired and entertained. And it's all free!
Heavy Metals in the Environment: Impact, Assessment, and Remediation synthesizes both fundamental concepts of heavy metal pollutants and state-of-the-art techniques and technologies for assessment and remediation. The book discusses the sources, origin and health risk assessment of heavy metals as well as the application of GIS, remote sensing and multivariate techniques in the assessment of heavy metals. The various contamination indices like contamination factor, geoaccumulation index, enrichment factor, and pollution index ecological risk index are also included to provide further context on the state of heavy metals in the environment. Covering a variety of approaches, techniques, and scenarios, this book is a key resource for environmental scientists and policymakers working to address environmental pollutants.
This book provides an in-depth discussion of various aspects of metal ecotoxicology. State-of-the-art information and techniques in areas ranging from metal behavior in surface waters to bioaccumulation kinetics and toxicokinetics to community effects are presented in a hierarchical arrangement. Specific topics discussed include metals in abiotic components of ecosystems, autecology (effects of metals relative to the individual or a single species), and metals in marine and freshwater systems in the context of synecology (species associated and interacting as a unit). This is an important book that will be useful to researchers, risk assessment consultants, regulatory personnel, and teachers and students.
This book addresses the three basic areas of combustion toxicology: combustion of materials, assessment of the toxicity of smoke, and understanding of hazards to humans. It is based on the papers published in the Journal of Fire Sciences during 1983-1987.
The inaugural volume in the Current Topics in Nonclinical Drug Development Series explores the critical issues and current topics in nonclinical drug development. This first volume covers individual topics and strategies in drug development from compound characterization to drug registration. Written by a variety of experts in the field, recent and rapid advances in technologies and associated changes in regulatory guidance are discussed. Additional features include: Deals with day-to-day issues in study design, evaluation of findings, and presentation of data. Explains new approaches in the development of medical devices. Includes dedicated chapters on the use of bioinformatics in drug development. Addresses strategies for photosafety testing of drugs. Current Topics in Nonclinical Drug Development, Volume I will aid toxicologists, toxicologic pathologists, consultants, regulators, Study Directors, and nonclinical scientists dealing with day-to-day issues in study design, evaluation of findings, and presentation of data. In addition, the book will be a valuable reference for academicians and graduate students pursuing research related to nonclinical drug development.
Insight into the role of hormones, particularly estrogen and testosterone, in health and disease etiology - including interactions with other hormone pathways - has dramatically changed. Estrogen and androgen receptors, with their polymorphisms, are key molecules in all tissues and are involved in a number of homeostatic mechanisms but also pathological processes including carcinogenesis and the development of metabolic and neurological disorders such as diabetes and Alzheimer's disease. Endocrine disrupting chemicals (EDCs) can interfere with the endocrine (hormone) systems at certain dosages and play a key role in the pathology of disease. Most known EDCs are manmade and are therefore an increasing concern given the number commonly found in household products and the environment. This book will cover the mechanisms of EDC pathology across the spectrum of disease, as well as risk assessment and government and legal regulation to provide a holistic view of the current issues and cutting-edge research in the topic. With contributions from global leaders in the field, this book will be an ideal reference for toxicologists, endocrinologists and researchers interested in developmental biology, regulatory toxicology and the interface between environment and human health.
Heavy metals and metalloids, singly or in combination, induce toxic manifestations either through acute or chronic pathology. In particular, long-term chronic exposure to diverse heavy metals and metalloids to humans and animals can lead to numerous physical, muscular, neurological, nephrological, and diverse degenerative diseases and dysfunctions, including multiple sclerosis, muscular dystrophy, Parkinson's and Alzheimer's diseases, cardiovascular disorders, and several others. Recognized heavy metals such as lead, mercury, arsenic, cadmium, thallium, and hexavalent chromium are known for enormous toxicity. The immediate vital signs of acute heavy metal exposure include nausea, vomiting, diarrhea, and acute abdominal pain. Mercury has been identified as the most toxic heavy metal, and mercury poisoning is known as acrodynia or pink disease. Similarly, lead, another toxic heavy metal, was at one time an integral part of painting. Metal Toxicology Handbook further explains and discusses the varying attributes of metals, discussing toxicity, safety, and proper human utilization of metals. Beginning with a broad overview of metals, metalloids, redox biology, and neurodegeneration and going further into the roles, benefits, and toxicity of metals with each section, the text contains 28 chapters from eminent researchers and scientists in their respective fields and is a must-have for anyone researching the potential toxicity in metals. Key Features Discusses the pathology of metal toxicity Highlights the benefits of metals Explains the mechanism and salient features of restoring metabolic homeostasis Highlights dose-dependent beneficial and adverse effects of vanadium safety and toxicity The initial introductory section provides a broad overview of metals, metalloids, redox biology, and neurodegeneration. The second section discusses the pathology of metal toxicity in two chapters, while the third section highlights the mechanism and salient features of restoring metabolic homeostasis in two chapters. The fourth section demonstrates the aspect of radionuclides toxicity. In a change of pace, the fifth section discusses the benefits of metals in four chapters. The sixth section, titled Toxic Manifestations by Diverse Heavy Metals and Metalloids, provides fourteen chapters that discuss the toxicological mechanism and manifestation of individual metals. The editors have crafted a commentary titled A Treatise on Metal Toxicity and summarized a vivid scenario of metal toxicity and its consequences.
Toxicology is a discipline that requires knowledge in many areas, such as analytical chemistry (organic and inorganic), biochemistry, pathology and physiology. This book is designed to provide a wide ranging, overview of the various toxicants and their effects on living organisms, particularly human begins. The book also examines the principles related to toxicology, chemical toxicology, environmental toxicology and related sciences. The book provides an up-to-date insight into the harmful interactions between chemicals (xenobiotics) and biological synthesis. It examines acute toxicology risk assessment, toxicity testing and many other areas directly or indirectly related to toxicology.
First Published in 1991, this book conducts a systematic analysis of existing information regarding the toxicological effects of pesticides on humans. The book identifies the negative health effects related to exposure to pesticides and the biological changes required to undertake biological monitoring. The book also discusses the importance and magnitude of the problem for different kinds of pesticide applications in different parts of the world, explains the toxicodynamics and clinical picture of acute and chronic intoxications resulting from exposure to different groups of pesticides and selected individual substances, and evaluates existing methods and limitations for assessing human exposure to pesticides. Pesticide manufacturers, occupational health professionals, epidemiologists, environmentalists, government agencies and others concerned with the effects of pesticides on human populations should consider this book essential reading.
Published in 1989: A comprehensive review of the chemical, clinical, pharmaco-logical, medical and social aspects of the chemicals that are widely abused is presented in this highly informative publication. The contributing authors represent expertise in clinical medicine, pharmacy, chemistry, pharmacology, social work and psychiatry. The scientific discussion, phar-macokinetic, pharmacological, and analytical, is well tied to the behavioral aspects of substances of abuse, making this a unique publication.
Published in 1983: Chromium is important in medicine because of its widespread use (about 400,000 tons are processed in the U.S. each year), toxicity, carcinogenic effect, and its high sensitization index in low concentration.
How can environmental regulators use information on 48-hour toxicity tests to predict the effects of a few minutes of pollution? Or, at the other extreme, what is the relevance of 96-hour toxicity data for organisms that may have been exposed to a pollutant for six months or more? Time to event methods are the key to answering these types of questions. Risk Assessment with Time to Event Models is the first comprehensive treatment of these methods in the context of ecological risk assessment. Leading experts from industry, academia, and government regulatory agencies explain how these methods can be used to extract more useful information from laboratory data than is present in simple summary statistics like 48-h LC50. The book offers a clear introduction to the field through several approaches, from the introductory to the more mathematical. Risk Assessment with Time to Event Models demonstrates the relevance of time in the analysis and reporting of toxicity data through the use of practical examples from the field of environmental toxicology. It also incorporates helpful analogies from other disciplines that commonly use time to event modeling.
This book provides a comprehensive understanding of a highly innovative method of natural wastewater treatment using advanced in-groundbioreactors called Eco-Engineered Bioreactors (EEBs), and traces their evolution from the earliest aerated gravel bed versions once known as Engineered Wetlands (EWs) and now known as BREW Bioreactors (BBRs) all the way to today's wide slate of aerobic and anaerobic varieties. Treatment using EEBs involves passing wastewaters through excavated basins in which they contact fixed films of microbial consortia on permeable substrate media. Written from the perspective of ecological engineers designing EEBs, this guide covers updated information on the state-of-the-art for EEBs, covering their morphologies, testing methods, designs, operations, and microbiology.