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See below for a selection of the latest books from Neurosciences category. Presented with a red border are the Neurosciences books that have been lovingly read and reviewed by the experts at Lovereading. With expert reading recommendations made by people with a passion for books and some unique features Lovereading will help you find great Neurosciences books and those from many more genres to read that will keep you inspired and entertained. And it's all free!
This book provides a unique overview on the most recent developments in initially diverse areas of behavioral genomic research that now start to intertwine to provide more detailed insights into the complex nature of behavior in health and disease. It focuses on our current understanding of genetic and epigenetic mechanisms of brain function and how they contribute to the complex formation of behavioral traits and psychiatric disorders. Readers experience diverse perspectives of the contributing authors starting from the genetic viewpoint and the effort to establish functional connection between genetic variants and behavioral phenotypes. Particular attention is given to the broad spectrum of epigenetic mechanisms and behavior. The chapter 'Role of MicoRNAs in Anxiety and Anxiety-Related Disorders' is available open access under a CC BY 4.0 license at link.springer.com
Of the research areas devoted to biomedical sciences, the study of the brain remains a field that continually attracts interest due to the vast range of people afflicted with debilitating brain disorders and those interested in ameliorating its effects. To discover the roots of maladies and grasp the dynamics of brain functions, researchers and practitioners often turn to a process known as brain source localization, which assists in determining the source of electromagnetic signals from the brain. Aiming to promote both treatments and understanding of brain ailments, ranging from epilepsy and depression to schizophrenia and Parkinson's disease, the authors of this book provide a comprehensive account of current developments in the use of neuroimaging techniques for brain analysis. Their book addresses a wide array of topics, including EEG forward and inverse problems, the application of classical MNE, LORETA, Bayesian based MSP, and its modified version, M-MSP. Within the ten chapters that comprise this book, clinicians, researchers, and field experts concerned with the state of brain source localization will find a store of information that can assist them in the quest to enhance the quality of life for people living with brain disorders.
This book is aimed at generating an updated reservoir of scientific endeavors undertaken to unravel the complicated yet intriguing topic of neurodegeneration. Scientists from Europe, USA and India who are experts in the field of neurodegenerative diseases have contributed to this book. This book will help readers gain insight into the recent knowledge obtained from Drosophila model, in understanding the molecular mechanisms underlying neurodegenerative disorders and also unravel novel scopes for therapeutic interventions. Different methodologies available to create humanized fly models that faithfully reflects the pathogenicities associated with particular disorders have been described here. It also includes information on the exciting area of neural stem cells. A brief discussion on neurofibrillary tangles, precedes the elaborate description of lessons learnt from Drosophila about Alzheimer's, Parkinson's, Spinomuscular Atrophy, Huntington's diseases, RNA expansion disorders and Hereditary Spastic Paraplegia. We have concluded the book with the use of Drosophila for identifying pharmacological therapies for neurodegenerative disorders. The wide range of topics covered here will not only be relevant for beginners who are new to the concept of the extensive utility of Drosophila as a model to study human disorders; but will also be an important contribution to the scientific community, with an insight into the paradigm shift in our understanding of neurodegenerative disorders. Completed with informative tables and communicative illustrations this book will keep the readers glued and intrigued. We have comprehensively anthologized the lessons learnt on neurodegeneration from Drosophila and have thus provided an insight into the multidimensional aspects of pathogenicities of majority of the neurodegenerative disorders.
Reveals an Emerging Avenue of Potential Treatments for a Host of Challenging Diseases and Disorders The H3 receptor is known to play a major role in a range of CNS disorders, including those affecting cognitive functions such as ADHD and Alzheimer's disease, as well as sleep disorders, obesity, epilepsy, schizophrenia, depression, and neurodegeneration. In light of dramatic advances in research at the molecular level, supported by impressive clinical studies, optimism remains high that an H3 receptor-related drug could hit the market soon. The Third Histamine Receptor: Selective Ligands as Potential Therapeutic Agents in CNS Disorders provides a thorough grounding in advances made over the last two decades. It brings together an elite group of 30 pioneering researchers. In writing about their own work, these scientists report on the cutting-edge investigations that are now being conducted across a variety of disciplines. This text is designed to aid researchers and inform those involved in the treatment and clinical aspects of a number of histamine-related diseases. Presents Several Disease-Specific Chapters Certainly, the most comprehensive and cutting-edge volume in the field, this text includes material drawn from groundbreaking research techniques and patent literature. Put together with great thought and passion, it is written to serve as a primary resource for anyone involved with or interested in the identification and localization of H3 receptors and the ligands being developed as therapeutic agents to treat a wide range of diseases including some that were once considered intractable.
This book offers a state-of-the-art report on recent discoveries concerning the basic and clinical, neuroscientific and psychiatric findings in depression research. Depressive disorder is a severe and recurrent brain disorder that can manifest in depressive mood, somatic symptoms and cognitive impairment. The underlying mechanisms of depressive disorder and its clinical practice are subjects of long-standing interests. This book is a biologically plausible and multilevel theory which describes neural, physiological, molecular and genomic mechanisms that drive depression pathogenesis, as well as navigates the clinical practice and management for depressive disorder. It mainly describes advances made over the past 20 years on the neural, molecular, neuroimaging, physiology, pathophysiology, pharmacology and internet-based measurement and management of depressive disorder. It will help postgraduate students and academic researchers to get either basic or clinical picture of depressive disorder. Also, it may benefit pharmaceutical companies for developing novel drugs to treat this disease.
This volume presents the latest methods and approaches used to better characterize the properties of the structural human brain, and also explores various dysfunctional and non-dysfunctional neuroanatomical variations. This book is divided into 3 parts: methods, non-clinical applications, and clinical applications. The chapters in Part 1 talk about methods to study cortical thickness and the general linear model. Part 2 covers changes in brain structure from birth to adulthood, and morphometry of the corpus callosum. Part 3 discusses applications to study Alzheimer's Disease, Parkinson's Disease, epilepsy, Schizophrenia, and suicide. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and comprehensive, Brain Morphometry is a valuable resource for students, clinicians, and researchers who are interested in this developing field.
This volume describes techniques to make synaptosomes, and discusses numerous ways that synaptosomes are used to study and answer diverse questions about synapses.After examining the history that led to making synaptosomes, the chapters delved into its important as a tool to explore synaptic connections. Some of the topics covered in this book are: synaptosome bioenergetics and glutamate release; affinity proteomics for interactome and phosphoproteome screening in synaptosomes; isolation of highly purified and functionally active synaptic mitochondria; and profiling of microRNA and protein from purified synaptoneurosomes in a neurodegenerative disease model. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and thorough, Synaptosomes is a valuable resource for any researcher interested in learning more about this developing field.
This authoritative volume contains 179 chapters by international experts on recent developments in our understanding of amyloid proteins, protein folding disorders, and new and proposed clinical trials in amyloidosis. Topics include detection and characterization techniques; biological functions; genetics; disorders, diagnosis, and treatments, including organ transplants and drug therapies; results from extensive clinical studies; and epidemiology. This is a valuable resource for clinicians who care for patients with systemic and localized forms of amyloidosis, and for researchers in biochemistry, neurobiology, and cell biology.
Mobile Brain-Body Imaging and the Neuroscience of Art, Innovation and Creativity is a trans-disciplinary, collective, multimedia collaboration that critically uncovers the challenges and opportunities for transformational and innovative research and performance at the nexus of art, science and engineering. This book addresses a set of universal and timeless questions with a profound impact on the human condition: How do the creative arts and aesthetic experiences engage the brain and mind and promote innovation? How do arts-science collaborations employ aesthetics as a means of problem-solving and thereby create meaning? How can the creative arts and neuroscience advance understanding of individuality and social cognition, improve health and promote life-long learning? How are neurotechnologies changing science and artistic expression? How are the arts and citizen science innovating neuroscience studies, informal learning and outreach in the public sphere? Emerging from the 2016 and 2017 International Conferences on Mobile Brain-Body Imaging and the Neuroscience of Art, Innovation and Creativity held in Cancun, Mexico and Valencia, Spain to explore these topics, this book intertwines disciplines and investigates not only their individual products-art and data-but also something more substantive and unique; the international pool of contributors reveals something larger about humanity by revealing the state of the art in collaboration between arts and sciences and providing an investigational roadmap projected from recent advances. Mobile Brain-Body Imaging and the Neuroscience of Art, Innovation and Creativity is written for academic researchers, professionals working in industrial and clinical centers, independent researchers and artists from the performing arts, and other readers interested in understanding emergent innovations at the nexus of art, science, engineering, medicine and the humanities. The book contains language, design features (illustrations, diagrams) to develop a conversational bridge between the disciplines involved supplemented by access to video, artistic presentations and the results of a hackathon from the MoBI conferences.
This book explains neural function at the level of ion channels and membrane excitability in neurons along the ascending auditory pathway. Airborne sound information is captured by the ears, transformed to neural electrical signals, and then processed in the brain. Readers will find full descriptions of these processes of signal transduction and transformation. First, it is described how, at the level of hair cells, the receptor cells in the cochlea, the sound-evoked vibration is transduced to electrical signals and transmitted to the auditory nerve fibers. In the second section it is explained how the electrical activity of these fibers is processed at the cochlear nucleus in order to extract the temporal and level information of sound separately and then transmitted to the third nucleus for processing of the interaural differences, such as the interaural time difference and the interaural level difference. The third section summarizes the transformation of auditory temporal information to the rate of neural firing activity in the midbrain and the higher nuclei, including the cortex, based on in vivo results. Finally, emerging new technologies to investigate auditory signal processing are reviewed and discussed.
Understanding and improving how organizations work and are managed is the object of management research and practice, and this topic is of longstanding interest in the academia and in society at large. More recently, the contribution that the study of the brain could make to, notably, our understanding of decisions, emotional reactions, and behaviors has led to the emergence of the field of organizational neuroscience . Within the field of management, organizational neuroscience seeks to explore linkages between neuroscience research, theories, and methods and management research. Its primary goal is to incorporate findings on the cognitive processes underlying the thoughts, behaviors and attitudes of organizational actors in order to better inform management theories, and to assist in understanding, predicting and improving these behaviors in the workplace. As a result, we have seen in the last decade a flurry of research projects and publications in organizational neuroscience, as well as novel or rejuvenated innovations around neuromarketing, neuroleadership, and cognitive enhancement in the work place, to name a few. However, research and practical applications in organizational neuroscience pose profound ethical challenges about, for example, organizational responsibility in the responsible use of scientific innovation. Drawing on recent debates in the field, and in response to upcoming ethical challenges of organization neuroscience, this book introduces organizational neuroethics as an emerging interdisciplinary field that addresses the ethics of organizational neuroscience research and applications, as well as the neuroscience of organizational ethics. The first part focuses on the ethics of organizational neuroscience and several chapters tackle the ethics of neuromarketing or neuroleadership and discuss the ethical issues associated with neuroenhancement practice in the workplace. The second part of the book addresses cutting-edge topics in the neuroscience of organizational ethics. Written by international experts in the fields of management, neuroscience, ethics, and social science, this book will be of prime interest to practitioners, researchers and students in the various fields concerned with improving management research and practices, as well as organizational ethics.