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See below for a selection of the latest books from Neurosciences category. Presented with a red border are the Neurosciences books that have been lovingly read and reviewed by the experts at Lovereading. With expert reading recommendations made by people with a passion for books and some unique features Lovereading will help you find great Neurosciences books and those from many more genres to read that will keep you inspired and entertained. And it's all free!
This book presents recent advances in pattern analysis of the human connectome. The human connectome, measured by magnetic resonance imaging at the macroscale, provides a comprehensive description of how brain regions are connected. Based on machine learning methods, multiviarate pattern analysis can directly decode psychological or cognitive states from brain connectivity patterns. Although there are a number of works with chapters on conventional human connectome encoding (brain-mapping), there are few resources on human connectome decoding (brain-reading). Focusing mainly on advances made over the past decade in the field of manifold learning, sparse coding, multi-task learning, and deep learning of the human connectome and applications, this book helps students and researchers gain an overall picture of pattern analysis of the human connectome. It also offers valuable insights for clinicians involved in the clinical diagnosis and treatment evaluation of neuropsychiatric disorders.
This book is the third in a series entitled, Compendium of In-Vivo Monitoring in Real-time Molecular Neuroscience. Its purpose is to provide a cross-section of research addressing monitoring in the rodent, and in some cases, the human brain.Detailed understanding of the neurobiology of the brain is demanding and involves increasingly wider scope of talent ranging from physicists, neurobiologists, chemists, molecular biologists and bioengineers. Coming from varied backgrounds, they do not necessarily understand how to formulate functional issues in a mutually understandable way. This aim of this book is to provide information which can serve as a starting point for understanding such a complex topic.The authors provide 'tutorial' writing for specialists, as well as material understandable to a wide audience including neuroscientists, those interested in drug discovery, and those using such measurements for diagnosis purposes.
This book reviews the scientific literature and the authors' own research linking aluminum neurotoxicity with cognitive impairment and Alzheimer's disease (AD). It focuses on aluminum levels in the brain, region-specific and subcellular distribution, and its relation to neurofibrillary tangles and amyloid beta. Further, the book stresses the importance of aluminum's complex speciation chemistry in relation to biology, and details aluminum's mechanism in oxidative stress and cell death, especially in connection with apoptosis and necroptosis. The electrophysiological variation and synaptic plasticity induced by aluminum are covered, while the metal's debatable role in AD and the cross-talk between aluminum and genetic susceptibility are also discussed. In closing, the book reviews the neurotoxic effects of aluminum and its important role in the pathogenesis of AD. Given its depth of coverage, the book provides readers with a systematic summary of aluminum neurotoxicity.
In this mind-bending book, an esteemed neuroscientist explains why perfectionism is pointless-and argues that mistakes, missteps, and flaws are the keys to success. Remember that time you screwed up simple math or forgot the name of your favorite song? What if someone told you that such embarrassing brain farts are actually secret weapons, proof of your superiority to computers and AI? In Scatterbrain, we learn that boredom awakens the muse, distractions spark creativity, and misjudging time creates valuable memories, among other benefits of our faulty minds. Throughout, award-winning neuroscientist Henning Beck's hilarious asides and brain-boosting advice make for delightful reading of the most cutting-edge neuroscience our brains will (maybe never) remember.
This volume explores the latest techniques and improved methods used to study important neurobiological and associated neuropathological conditions. Chapters cover topics such as the application of semiconductor quantum dots as photostable fluorophores used for labeling and tracking; GCaMP6 transcranial imaging to monitor neural activity; the patch-clamping technique allowing simultaneous monitoring of membrane currents and optical signals; and quantifying behavioral dysfunction caused by traumatic brain injury (TBI). In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and practical, Basic Neurobiology Techniques is a valuable resource for novel and expert researchers interested in expanding their knowledge of this developing field.
This volume covers the latest techniques and strategies used in multi-photon excitation (MPE) microscopy. Chapters in this book cover the fundamentals of MPE microscopy as applied to both in vitro and in vivo experimental systems; information on how to combine MPE microscopy with targeted electrophysiological recordings, calcium imaging, and transmembrane voltage imaging; methods to investigate cellular and large-scale neural morphology; signaling in astrocytes; and ways to use MPE microscopy to study the retina. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Comprehensive and thorough, Multiphoton Microscopy is a valuable resource for both expert and novice researchers interested in expanding their knowledge and research in this rapidly developing field.
Stress Resilience: Molecular and Behavioral Aspects presents the first reference available on the full-breadth of cutting-edge research being carried out in this field. It includes a wide range of basic molecular knowledge on the potential associations between resilience phenomenon and biochemical balance, but also focuses on the molecular and cellular mechanisms underlying stress resilience. World-renowned experts provide chapters that cover everything from the neural circuits of resilience, the effects of early-life adversity, and the transgenerational inheritance of resilience. This unique and timely book will be a go-to resource for neuroscientists and biological psychiatrists who want to improve their understanding of the consequences of stress and on how some people are able to avoid it.
How our intuitive understanding of numbers is deeply rooted in our biology, traceable through both evolution and development. Humans' understanding of numbers is intuitive. Infants are able to estimate and calculate even before they learn the words for numbers. How have we come to possess this talent for numbers? In A Brain for Numbers, Andreas Nieder explains how our brains process numbers. He reports that numerical competency is deeply rooted in our biological ancestry; it can be traced through both the evolution of our species and the development of our individual minds. It is not, as it has been traditionally explained, based on our ability to use language. We owe our symbolic mathematical skills to the nonsymbolic numerical abilities that we inherited from our ancestors. The principles of mathematics, Nieder tells us, are reflections of the innate dispositions wired into the brain. Nieder explores how the workings of the brain give rise to numerical competence, tracing flair for numbers to dedicated number neurons in the brain. Drawing on a range of methods including brain imaging techniques, behavioral experiments, and twin studies, he outlines a new, integrated understanding of the talent for numbers. Along the way, he compares the numerical capabilities of humans and animals, and discusses the benefits animals reap from such a capability. He shows how the neurobiological roots of the brain's nonverbal quantification capacity are the evolutionary foundation of more elaborate numerical skills. He discusses how number signs and symbols are represented in the brain; calculation capability and the neuromythology of mathematical genius; the start-up tools for counting and developmental of dyscalculia (a number disorder analogous to the reading disorder dyslexia); and how the brain processes the abstract concept of zero.
This book focuses on our current understanding of brain dynamics in various brain disorders (e.g. epilepsy, Alzheimer's and Parkinson's disease) and how the multi-scale, multi-level tools of computational neuroscience can enhance this understanding. In recent years, there have been significant advances in the study of the dynamics of the disordered brain at both the microscopic and the macroscopic levels. This understanding can be furthered by the application of multi-scale computational models as integrative principles that may link single neuron dynamics and the dynamics of local and distant brain regions observed using human EEG, ERPs, MEG, LFPs and fMRI. Focusing on the computational models that are used to study movement, memory and cognitive disorders as well as epilepsy and consciousness related diseases, the book brings together physiologists and anatomists investigating cortical circuits; cognitive neuroscientists studying brain dynamics and behavior by means of EEG and functional magnetic resonance imaging (fMRI); and computational neuroscientists using neural modeling techniques to explore local and large-scale disordered brain dynamics. Covering topics that have a significant impact on the field of medicine, neuroscience and computer science, the book appeals to a diverse group of investigators.
This book discusses the latest research into the highly prevalent neurodevelopmental disease most commonly associated with aging: Alzheimer's disease (AD). Even after years of research, Alzheimer's disease is still far from being cured. It presents a range of common symptoms in the form of behavioral and cognitive impairments. This book describes the symptoms and the biology behind them. The contents covers latest findings on the genetics involved and various factors and pathways influencing disease development. It also covers various non-pharmacological therapies like immunotherapy, use of natural products, and employing nanotechnology in both the detection and treatment of AD. This book also highlights the role of diet and nutrition in healthy aging. Given its scope, it offers a valuable asset for researchers and clinicians alike.
Based on a foundation of science and empirical observation, engineering research and design has brought science fiction into science fact. The convergence of neuroscience and technology is facilitating the development of therapies that not long ago would have seemed unimaginable, if not impossible. With contributions from pioneers in industry, academia, and clinical medicine, Neuroengineering provides an understanding of the history, physiology and the most promising engineering technologies. The book presents clinical applications of neuromodulation and a detailed review of the science and mechanisms of action underlying deep brain stimulation. Contributions include discussions of seizure control, clinical, surgical, and technological aspects of responsive neurostimulation, and a thorough review of spinal cord stimulation for pain control. The book highlights promising technologies and applications for neural augmentation, brain and computer interfaces, and motor protheses. It concludes with coverage of the science underlying current neurostimulation techniques and new paradigm-shifting neuromodulation technologies. We are on the cusp of a technological revolution that promises to have more of an impact on human health, disease, and quality of life than any other in recent history. Its impact on medicine and society promises to be as dramatic as that of the development of antibiotics. The transition of neural engineering from basic research to intense commercialization and widespread clinical application and acceptance is just around the corner. Providing in-depth coverage of cutting-edge developments in technology and clinical practice, the book presents detailed descriptions of technologies, science, and clinical results that build a foundation for the future.
Neuronal communication forms the basis for all behavior, from the smallest movement to our grandest thought processes. Among the many mechanisms that support these functions, spike timing is among the most powerful and-until recently-perhaps the least studied. In the last two decades, however, the study of spike timing has exploded. The heightened interest is due to several factors. These include the development of physiological tools for measuring the activity of neural ensembles and analytical tools for assessing and characterizing spike timing. These advances are coupled with a growing appreciation of spike timing's theoretical importance for the design principles of the brain. Spike Timing: Mechanisms and Function examines the function of spike timing in sensory, motor, and integrative processes, providing readers with a broad perspective on how spike timing is produced and used by the nervous system. It brings together the work and ideas of leaders in the field to address current thinking as well as future possibilities. The first section of the book describes the foundation for quantitative analysis and theory. It examines the information contained in spike timing, how it can be quantified, and how neural systems can extract it. The second section explores how input-output relationships are reflected in spike timing across a range of sensory systems. Drawing together multiple perspectives, including theoretical and computational studies as well as experimental studies in a range of model systems, the book provides a firm background for investigators to consider spike timing as it applies to their own work. It also offers a glimpse of future advances related to mechanisms of spike timing and its role in neural function, such as the development of novel computational technologies.