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Neurosciences

See below for a selection of the latest books from Neurosciences category. Presented with a red border are the Neurosciences books that have been lovingly read and reviewed by the experts at Lovereading. With expert reading recommendations made by people with a passion for books and some unique features Lovereading will help you find great Neurosciences books and those from many more genres to read that will keep you inspired and entertained. And it's all free!

The Cognitive Neurosciences

The Cognitive Neurosciences

Author: Sarah-Jayne Blakemore Format: Hardback Release Date: 10/03/2020

The sixth edition of the foundational reference on cognitive neuroscience, with entirely new material that covers the latest research, experimental approaches, and measurement methodologies. Each edition of this classic reference has proved to be a benchmark in the developing field of cognitive neuroscience. The sixth edition of The Cognitive Neurosciences continues to chart new directions in the study of the biological underpinnings of complex cognition-the relationship between the structural and physiological mechanisms of the nervous system and the psychological reality of the mind. It offers entirely new material, reflecting recent advances in the field, covering the latest research, experimental approaches, and measurement methodologies. This sixth edition treats such foundational topics as memory, attention, and language, as well as other areas, including computational models of cognition, reward and decision making, social neuroscience, scientific ethics, and methods advances. Over the last twenty-five years, the cognitive neurosciences have seen the development of sophisticated tools and methods, including computational approaches that generate enormous data sets. This volume deploys these exciting new instruments but also emphasizes the value of theory, behavior, observation, and other time-tested scientific habits. Section editors Sarah-Jayne Blakemore and Ulman Lindenberger, Kalanit Grill-Spector and Maria Chait, Tomas Ryan and Charan Ranganath, Sabine Kastner and Steven Luck, Stanislas Dehaene and Josh McDermott, Rich Ivry and John Krakauer, Daphna Shohamy and Wolfram Schultz, Danielle Bassett and Nikolaus Kriegeskorte, Marina Bedny and Alfonso Caramazza, Liina Pylkkanen and Karen Emmorey, Mauricio Delgado and Elizabeth Phelps, Anjan Chatterjee and Adina Roskies

Brain Mitochondria Distribution and Function

Brain Mitochondria Distribution and Function

Author: Silvia Lores-Arnaiz Format: Hardback Release Date: 09/03/2020

Brain mitochondria: Distribution and Function offers an overview of significant findings regarding physiological, toxicological and pathological aspects of brain mitochondria properties and their relevant role in cellular bioenergetics. Essential physiological processes such as cell respiration and ATP synthesis, the maintenance of calcium homeostasis, reactive oxygen species generation and apoptotic cell signaling performed by mitochondria are described in the different chapters of this volume. In particular, the importance of specific calcium signaling at synaptic level and its relationship with mitochondrial bioenergetics are extensively described. Being that high energy demands are required at synaptic level for neurotransmission, mitochondrial distribution becomes relevant for essential neuronal processes. Differential bioenergetic characteristics of neuronal, astrocytic and glial mitochondria are discussed. Interestingly, new insights on the interaction between neurotensinergic and nitrergic systems are detailed, based on experimental evidences of the effect of neurotensin receptors blockade on nitric oxide production and mitochondrial function. The chapters describing metal neurotoxicity provide a comprehensive view of the effects of different metals on brain mitochondrial function and their consequences for human health. The impact of iron and copper overload on brain oxidative redox balance and mitochondrial function is fully detailed, focusing on the role of metal-induced neuronal damage on the incidence and progression of neurodegenerative diseases. In addition, a complete revision of the mechanisms underlying heavy metal-mediated damage to brain mitochondria is presented. Neurotoxic effects of arsenic, thallium, lead, cadmium and mercury have been associated with cell bioenergetics impairment, exacerbated production of oxygen free radicals, and induction of intrinsic pathway of apoptosis. Mitochondrial function can also be impaired by treatment with different drugs acting at CNS level. The understanding of the effects of pharmacological agents, abuse drugs, herbicides and insecticides at mitochondrial level can contribute to elucidate the molecular mechanisms involved in neurodegeneration. In this context, the neuroprotective effect of different compounds targeting mitochondrial integrity and function is discussed. Furthermore, mitochondrial alterations, oxygen radicals generation and nitric oxide production are characterized in relation to CNS pathology and hypoxia conditions. Mitochondrial complex I inactivation, oxidative stress and impairment of mitochondrial nitric oxide synthesis are characteristic features of the mitochondrial dysfunction observed in Parkinson's disease and other CNS pathologies. In addition, exposure to hypoxic conditions can affect nitric oxide generation and mitochondrial physiology, with different responses depending on the brain area. As a whole, the understanding of the alterations in mitochondrial distribution and function in the brain associated with neurotoxicity and neurodegeneration may contribute to the knowledge of the role of mitochondria in maintaining the balance between health and disease.

Wayfinding The Art and Science of How We Find and Lose Our Way

Wayfinding The Art and Science of How We Find and Lose Our Way

Author: Michael Bond Format: Paperback / softback Release Date: 05/03/2020

The physical world is infinitely complex, yet most of us are able to find our way around it. We can walk through unfamiliar streets while maintaining a sense of direction, take shortcuts along paths we have never used and remember for many years places we have visited only once. These are remarkable achievements. In Wayfinding, Michael Bond explores how we do it: how our brains make the 'cognitive maps' that keep us orientated, even in places that we don't know. He considers how we relate to places, and asks how our understanding of the world around us affects our psychology and behaviour. The way we think about physical space has been crucial to our evolution: the ability to navigate over large distances in prehistoric times gave Homo sapiens an advantage over the rest of the human family. Children are instinctive explorers, developing a spatial understanding as they roam. And yet today few of us make use of the wayfaring skills that we inherited from our peripatetic ancestors. Most of us have little idea what we may be losing. Bond seeks an answer to the question of why some of us are so much better at finding our way than others. He also tackles the controversial subject of sex differences in navigation, and finally tries to understand why being lost can be such a devastating psychological experience. For readers of writers as different as Robert Macfarlane and Oliver Sacks, Wayfinding is a book that can change our sense of ourselves.

Wayfinding The Art and Science of How We Find and Lose Our Way

Wayfinding The Art and Science of How We Find and Lose Our Way

Author: Michael Bond Format: Hardback Release Date: 05/03/2020

The physical world is infinitely complex, yet most of us are able to find our way around it. We can walk through unfamiliar streets while maintaining a sense of direction, take shortcuts along paths we have never used and remember for many years places we have visited only once. These are remarkable achievements. In Wayfinding, Michael Bond explores how we do it: how our brains make the 'cognitive maps' that keep us orientated, even in places that we don't know. He considers how we relate to places, and asks how our understanding of the world around us affects our psychology and behaviour. The way we think about physical space has been crucial to our evolution: the ability to navigate over large distances in prehistoric times gave Homo sapiens an advantage over the rest of the human family. Children are instinctive explorers, developing a spatial understanding as they roam. And yet today few of us make use of the wayfaring skills that we inherited from our peripatetic ancestors. Most of us have little idea what we may be losing. Bond seeks an answer to the question of why some of us are so much better at finding our way than others. He also tackles the controversial subject of sex differences in navigation, and finally tries to understand why being lost can be such a devastating psychological experience. For readers of writers as different as Robert Macfarlane and Oliver Sacks, Wayfinding is a book that can change our sense of ourselves.

The Man Who Wasn't There Tales from the Edge of the Self

The Man Who Wasn't There Tales from the Edge of the Self

Author: Anil Ananthaswamy Format: Paperback / softback Release Date: 05/03/2020

Reveals the mind boggling neuroscience connecting brain, body, mind, and society, by examining a range of brain disorders, in the tradition of Oliver Sacks. Identifying what makes up the nature of the human mind has long been neuroscience's greatest challenge - a mystery perhaps never to be fully understood. Award-winning author and master of science journalism Anil Ananthaswamy smartly explores the concept of self by way of several mental conditions that alter patients' identities, showing how we learn a lot about being human from people with a fragmented or altered sense of self. He travels the world to meet those who suffer from maladies of the self interviewing patients, psychiatrists, philosophers and neuroscientists along the way. He charts how the self is affected by Asperger's, autism, Alzheimer's, epilepsy, schizophrenia, among many other mental conditions, revealing how the brain constructs our sense of self. Each chapter is anchored with stories of people who experience themselves differently from the norm. The Man Who Wasn't There is a magical mystery tour of scientific analysis and philosophical pondering, now utterly transformed by recent advances in cutting-edge neuroscience. ***PRAISE FOR THE MAN WHO WASN'T THERE*** 'Ananthaswamy excels at making theoretical concepts and experimental procedures both comprehensible and compelling.' Science 'If you simply want to read a great science book, I can't recommend any more highly than this one.' Forbes 'A compelling and entertaining look at the last untapped mystery, the true final frontier: the nature of our selves. Science journalism at its best.' Daniel J. Levitin, author of The Organized Mind 'An agreeably written travelogue through this mysterious landscape at the frontiers of knowledge.' The Wall Street Journal 'You'll never see yourself-or others-the same way again.' People 'Ananthaswamy's remarkable achievement is to make sense of these unhappy individuals' otherness, while holding on to their human sameness. You'll come away enlightened and chastened, asking searching questions about who you are.' Nicholas Humphrey, author of A History of the Mind 'It is an astonishing journey and an ambitious book, bringing together cutting-edge science and philosophy from West and East. You will not be quite the same self after reading it.' New Scientist

Functional and Clinical Neuroanatomy A Guide for Health Care Professionals

Functional and Clinical Neuroanatomy A Guide for Health Care Professionals

Functional and Clinical Neuroanatomy: A Guide for Health Care Professionals is a comprehensive, yet easy-to read, introduction to neuroanatomy that covers the structures and functions of the central, peripheral and autonomic nervous systems. The book also focuses on the clinical presentation of disease processes involving specific structures. It is the first review of clinical neuroanatomy that is written specifically for nurses, physician assistants, nurse practitioners, medical students and medical assistants who work in the field of neurology. It will also be an invaluable resource for graduate and postgraduate students in neuroscience. With 22 chapters, including two that provide complete neurological examinations and diagnostic evaluations, this book is an ideal resource for health care professionals across a wide variety of disciplines.

A Closer Look at Neurotoxicity

A Closer Look at Neurotoxicity

Author: Gokul Krishna Format: Paperback / softback Release Date: 26/02/2020

This book details neurotoxicology research about the neurotoxic effects of substances on the young, adult or aging nervous system. Chapters (both review and original research papers) about the epidemiological reports, animal research, in vitro adverse effects of toxic agents on neurodevelopment and mature nervous systems are included. Neurotoxicity contributes to pathogenesis of neurodevelopmental, neurobehavioral, and neurodegenerative disorders. The chapters provide a basic foundation on the significant outcome effects on current knowledge in neurotoxicity research.

The True Creator of Everything How the Human Brain Shaped the Universe as We Know It

The True Creator of Everything How the Human Brain Shaped the Universe as We Know It

Author: Miguel Nicolelis Format: Hardback Release Date: 25/02/2020

A radically new cosmological view from a groundbreaking neuroscientist placing the human brain at the center of humanity's universe Renowned neuroscientist Miguel Nicolelis introduces readers to a revolutionary new theory of how the human brain evolved to become an organic computer without rival in the known universe. Nicolelis undertakes the first attempt to explain the entirety of human history, culture, and civilization based on a series of recently uncovered key principles of brain function. This new cosmology is centered around three fundamental properties of the human brain: its insurmountable malleability to adapt and learn; its exquisite ability to allow multiple individuals to synchronize their minds around a task, goal, or belief; and its incomparable capacity for abstraction. Combining insights from such diverse fields as neuroscience, mathematics, evolution, computer science, physics, history, art, and philosophy, Nicolelis presents a neurobiologically based manifesto for the uniqueness of the human mind and a cautionary tale of the threats that technology poses to present and future generations.

Electric Brain How the New Science of Brainwaves Reads Minds, Tells Us How We Learn, and Helps Us Change for the Better

Electric Brain How the New Science of Brainwaves Reads Minds, Tells Us How We Learn, and Helps Us Change for the Better

Author: R. Douglas Fields Format: Hardback Release Date: 20/02/2020

What is as unique as your fingerprints and more revealing than your diary? Hint: Your body is emitting them right now and has been every single day of your life. Brainwaves. Analyzing brainwaves, the imperceptible waves of electricity surging across your scalp, has been possible for nearly a century. But only now are neuroscientists becoming aware of the wealth of information brainwaves hold about a person's life, thoughts, and future health. From the moment a reclusive German doctor discovered waves of electricity radiating from the heads of his patients in the 1920s, brainwaves have sparked astonishment and intrigue, yet the significance of the discovery and its momentous implications have been poorly understood. Now, it is clear that these silent broadcasts can actually reveal a stunning wealth of information about any one of us. In Electric Brain, world-renowned neuroscientist and author R. Douglas Fields takes us on an enthralling journey into the world of brainwaves, detailing how new brain science could fundamentally change society, separating fact from hyperbole along the way. In this eye-opening and in-depth look at the most recent findings in brain science, Fields explores groundbreaking research that shows brainwaves can: Reveal the type of brain you have-its strengths and weaknesses and your aptitude for learning different types of information Allow scientists to watch your brain learn, glean your intelligence, and even tell how adventurous you are Expose hidden dysfunctions-including signifiers of mental illness and neurological disorders Render your thoughts and transmit them to machines and back from machines into your brain Meld minds by telepathically transmitting information from one brain to another Enable individuals to rewire their own brains and improve cognitive performance Written by one of the neuroscientists on the cutting edge of brainwave research, Electric Brain tells a fascinating and obscure story of discovery, explains the latest science, and looks to the future-and the exciting possibilities in store for medicine, technology, and our understanding of ourselves.

Neurosecretion: Secretory Mechanisms

Neurosecretion: Secretory Mechanisms

Author: Jose Lemos Format: Hardback Release Date: 04/02/2020

How do electrical activity and calcium signals in neurons influence the secretion of peptide hormones? This volume presents the current state of knowledge regarding the electrical, calcium signaling and synaptic properties of neuroendocrine systems from both vertebrate and invertebrate systems. The contributions span in vivo and in vitro studies that address: state-dependent plasticity, relevance of firing patterns, membrane properties, calcium flux (including dynamic imaging and homeostasis), and molecular mechanisms of exocytosis, including from non-neuronal secretory cells. The chapters focus not only on research results but also on how experiments are conducted using state-of-the-art techniques, and how the resulting data are interpreted. While there are many books on the secretory properties of neurons, this is the first to focus on the distinctive secretory properties of neuroendocrine neurons. Accordingly, it offers an important text for undergraduate and graduate neuroscience students, and will also appeal to established scientists and postdoctoral fellows. This is the eighth volume in the Masterclass in Neuroendocrinology Series- now a co-publication between Springer-Nature and the INF (International NeuroendocrineFederation).

Insights into Human Neurodegeneration: Lessons Learnt from Drosophila

Insights into Human Neurodegeneration: Lessons Learnt from Drosophila

Author: Mousumi Mutsuddi Format: Hardback Release Date: 04/02/2020

This book is aimed at generating an updated reservoir of scientific endeavors undertaken to unravel the complicated yet intriguing topic of neurodegeneration. Scientists from Europe, USA and India who are experts in the field of neurodegenerative diseases have contributed to this book. This book will help readers gain insight into the recent knowledge obtained from Drosophila model, in understanding the molecular mechanisms underlying neurodegenerative disorders and also unravel novel scopes for therapeutic interventions. Different methodologies available to create humanized fly models that faithfully reflects the pathogenicities associated with particular disorders have been described here. It also includes information on the exciting area of neural stem cells. A brief discussion on neurofibrillary tangles, precedes the elaborate description of lessons learnt from Drosophila about Alzheimer's, Parkinson's, Spinomuscular Atrophy, Huntington's diseases, RNA expansion disorders and Hereditary Spastic Paraplegia. We have concluded the book with the use of Drosophila for identifying pharmacological therapies for neurodegenerative disorders. The wide range of topics covered here will not only be relevant for beginners who are new to the concept of the extensive utility of Drosophila as a model to study human disorders; but will also be an important contribution to the scientific community, with an insight into the paradigm shift in our understanding of neurodegenerative disorders. Completed with informative tables and communicative illustrations this book will keep the readers glued and intrigued. We have comprehensively anthologized the lessons learnt on neurodegeneration from Drosophila and have thus provided an insight into the multidimensional aspects of pathogenicities of majority of the neurodegenerative disorders.

Preclinical Research in Down Syndrome: From Bench to Bedside

Preclinical Research in Down Syndrome: From Bench to Bedside

Author: Mara (CRG-Center for Genomic Regulation, Spain) Dierssen Format: Hardback Release Date: 01/02/2020

Preclinical Research in Down Syndrome: From Bench to Bedside, Volume 251, the latest release in the Progress in Brain Research series, highlights new advances in the field. Chapters in this updated release include Exploring genetic and epigenetic mechanisms underlying cognitive deficits in Dow syndrome, The trisomy paradox: gene expression dysregulation domains, the Influence of allelic differences in mouse models of Down syndrome, Modelling Down syndrome in cells: From stem cells to organoids, Modelling Down syndrome in animals from the early stage to the new generation of models, Mapping behavioral landscapes in Down syndrome animal models, and more.