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Xenobiotics

See below for a selection of the latest books from Xenobiotics category. Presented with a red border are the Xenobiotics books that have been lovingly read and reviewed by the experts at Lovereading. With expert reading recommendations made by people with a passion for books and some unique features Lovereading will help you find great Xenobiotics books and those from many more genres to read that will keep you inspired and entertained. And it's all free!

Exchangers

Exchangers

Current Topics in Membranes is targeted toward scientists and researchers in biochemistry and molecular and cellular biology, providing the necessary membrane research to assist them in understanding the current state and future prospects of a particular field. This volume on exchangers, in conjunction with a previous volume on cotransporters (volume 70), represents an up-to-date, systematic, and comprehensive review of all the major secondary active carrier proteins responsible for the absorption, secretion, and general transport of ions and solutes in mammalian organ systems and additional species. Each chapter is devoted to a specific transporter or a grouping of related transporters based on the well-recognized nomenclature of the SoLute Carrier (SLC) gene family. This book provides readers with the latest mechanistic information on the function and structure of specific transporters, as well as their history and physiological significance.

Handbook on Reactive Oxygen Species (ROS) Formation Mechanisms, Physiological Roles & Common Harmful Effects

Handbook on Reactive Oxygen Species (ROS) Formation Mechanisms, Physiological Roles & Common Harmful Effects

Author: Masa Suzuki Format: Hardback Release Date: 24/03/2014

In this handbook, the authors present topical research in the study of the formation mechanisms, physiological roles and common harmful effects of reactive oxygen species (ROS). Topics discussed in this compilation include the role of mitochondria in the generation of ROS; reactive oxygen species in cyanobacteria; participation of ROS in the formation of induced resistances of plants to abiotic stressors; ROS and autoimmune diseases; metal oxide nanoparticles as a source for ROS and their application in the fabrication of antimicrobial textiles; the synergistic effect of photocatalytic water purification with ROS; oxidative stress on neurodegeneration and its implications in Alzheimer's and Parkinson's disease; the interplay between ROS and gaseous messenger molecules in plant response to environmental stresses; ROS in non-invasive cancer therapy; oxidative stress in the lungs and blood induced by smoking and exercise; plant signalling networks involving reactive oxygen species and Ca2+; free radicals and the role of antioxidant enzymes on ionising radiation resistance in zygophyllum fabago, phragmites australis, argusia sibirica L., and eleagnus caspica plants; reactive oxygen species and wound healing; and gender dimorphism in hepatic oxidative stress induced by protein malnutrition during pregnancy and childhood.

New Research on Protein Synthesis

New Research on Protein Synthesis

Author: Carlo Bethaz Format: Paperback / softback Release Date: 01/03/2014

In this book, the authors present current research from across the globe in the study of protein synthesis. Topics discussed in this compilation include protein synthesis elongation factors EF-Tu and eEF1A and their application in the improvement of heat tolerance in plants; myostatin function in muscle protein homeostasis and its link with the regulation of translation; and energy regeneration systems in cell free protein in vitro.

Acetic Acids Chemical Properties, Production & Applications

Acetic Acids Chemical Properties, Production & Applications

Author: Angelo Basile Format: Hardback Release Date: 02/02/2014

This book provides some important aspects of acetic acid, especially those concerning its recent use and applications, including the fermentation process of ethanol with acetic acid bacteria, its use in meat preservation, medicinal effects of acetic acid, as well as health and safety considerations. Other aspects include the properties of auxins, an important category of acetic acids influencing a number of physiological and developmental processes in plants, the characterisation of the synthesis, structural and vibrational properties of three quinoline acetic acid derivatives with potential biological activities and the use of acetic acid in food preparation/production and the co-production of vinegar and electricity through fermentation.

Recent Advances in Proteomics Research

Recent Advances in Proteomics Research

Author: Ming D. Li Format: Hardback Release Date: 31/01/2014

The primary objective of this book is to provide updated knowledge of recent advances in proteomics research in various fields. The topics covered include, but are not limited to, proteomic analysis for microbiomes, specific cell types from heterogeneous tissues, body fluids, mitochondria, and environmental toxicology. Almost all proteomics techniques currently used in research have been reviewed in at least one chapter, including traditional one- or two-dimensional gel-based, gel-free shotgun, label-based or labelfree quantitative, and array-based methods. In addition, although they are not the major focus of this book, proteomics-related bioinformatics tools such as database searching, data mining, data analysis, and gene pathway analysis are briefly covered. Additionally, this book contains chapters on some technical issues related to applying proteomics technologies to specific issues, such as sample preparation for removal of contaminants and depletion of highly abundant proteins. Collectively, these chapters provide a broad view of various technologies commonly used in proteomics research and their successful applications to address different questions across various species. It is our hope that such a book can provide readers with a comprehensive understanding of proteomics technologies and their application to address various scientific questions.

Inhibitors of the Ras Superfamily G-proteins, Part B

Inhibitors of the Ras Superfamily G-proteins, Part B

Targeted toward researchers in biochemistry, molecular and cell biology, pharmacology, and cancer, this is the second part of The Enzymes' volumes that discuss inhibitors of the Ras superfamily G-proteins.

Molecular & Supramolecular Bioinorganic Chemistry Applications in Medical & Environmental Sciences -- Volume 4

Molecular & Supramolecular Bioinorganic Chemistry Applications in Medical & Environmental Sciences -- Volume 4

Author: Ana Lucia Ramalho Merce Format: Hardback Release Date: 01/12/2013

An immense amount of human knowledge that has been collected for ages currently exists. Nonetheless, the quest for the cure of some dire diseases, many of them fatal, is needed now more than ever. It seems that the main focus is not to state consequences, but to find causes. Taking the hypercomplexity of human biochemistry and physiology into consideration, as well as the multitude of existing scientific reports in the literature at present, this knowledge is vast enough to spend a lifetime studying, if anyone were willing to do so. This information will then pave the way to even more research in any field of science, regardless of being old-fashioned, forgotten or even discredited by some of the scientific representatives that would certainly be labelled as deceivers of humanity for leaving us with fewer choices, thus restraining our right to choose what is best for ourselves. Science is boundless, and therefore, all research should be free of any interference, for example, on how and if a research study should be conducted until the results are presented. That was not the case with the last centuries' scientists; back then, both their laboratories and lives were in danger. In honour of those who stand for free science, this volume presents the knowledge as it should be, as an open source to anyone, and where it leads us is our own decision entirely. This is the fourth volume in our series.

Oligosaccharides Food Sources, Biological Roles & Health Implications

Oligosaccharides Food Sources, Biological Roles & Health Implications

Author: Lori S. Schweizer Format: Hardback Release Date: 01/12/2013

In this book, the authors present current research in the study of the food sources, biological roles and health implications of oligosaccharides. Topics discussed in this compilation include functional oligosacchardes and their positive health benefits on the digestive system; prebiotic oligosaccharides; the role of human milk oligosaccharides in preventing respiratory infections in infants; alterations in the glycosylation patterns of alpha-1 glycoprotein in the diagnostic detection of breast cancer; production of oligosaccharides with low molecular weights, secoiridoids and phenolic glycosides from thermally treated olive by-products; supramolecular analytical applications of cyclodextrins and their derivatives using fluorescence spectroscopy; utilisation of soy oligosaccharides during fermentation by lactobacilli; impact of low oligosaccharide soybean meal on nutrient digestibility, growth performance, and carcass characteristics of broiler chickens; lipo-oligosaccharides in Miller Fisher Syndrome; and oligosaccharides from ancient beverages fermented by symbiotic cultures.

Inhibitors of the Ras Superfamily G-proteins, Part A

Inhibitors of the Ras Superfamily G-proteins, Part A

This special volume of The Enzymes is targeted toward researchers in biochemistry, molecular and cell biology, pharmacology, and cancer. This thematic volume discusses inhibitors of the Ras superfamily G-proteins.

Marine Medicinal Glycomics

Marine Medicinal Glycomics

Author: Vitor Hugo Pomin Format: Hardback Release Date: 01/07/2013

Glycomics is an international project that analyses systematically and comparatively the overall and/or specific structural and biological properties of carbohydrates, also known as sugars or glycans, within a repertoire from a given type of cell, tissue, organism, kingdom, or even from a certain environment, as found under specific conditions. Glycomics is one of the latest omics projects to be launched into biology. This was because carbohydrates had been primarily considered as a mere class of structural or energetic molecules. Besides that, structural and functional studies in glycomics are more challenging than other projects, and analytical limitations in glycobiology have impaired the progress. However, with the development of technology, and mostly through recent scientific achievements, innumerous vital biological functions have been uncovered and attributed to the sugars. Moreover, certain glycans may also exhibit effective medicinal properties which have in turn awakened a great interest by pharmaceutical companies. This book compiles and illustrates some of these recent achievements concerning the principle examples of marine sugars with medical properties, such as chitin, chitosan, sulphated polysaccharides, and glycoconjugates. Their therapeutic actions are very broad since they comprise beneficial effects in many systems such as inflammation, coagulation, thrombosis, cancer growth/metastasis, and vascular biology. Additional information about the enzymatic synthesis, chemically modified derivatives, relevance of composing units, and other biochemical properties of these marine medicinal glycans are also discussed herein.

Biotransformation and Metabolite Elucidation of Xenobiotics Characterization and Identification

Biotransformation and Metabolite Elucidation of Xenobiotics Characterization and Identification

Author: Ala F. Nassar Format: Hardback Release Date: 12/11/2010

The goal of this book is to improve the readers' knowledge of metabolite elucidation in drug metabolism by exposing them to in depth coverage of the biotransformation of xenobiotics, strategies for identifying and characterizing metabolites, FDA guidelines, and case studies on how to improve the decision-making process in structural modification of drug candidates to reduce toxicity. The book consists of 8 chapters; it first provides an introduction on biotransformation of xenobiotics, and then presents modern approaches and strategies for dealing with metabolite characterization, using tools such as LC-MS, H-D exchange, stable isotopes LC-MS-NMR, and radiolabeled compounds. Also, strategies for dealing with reactive intermediates in drug discovery and development are presented as well as case studies on improving the decision-making process in the structural modification of drug candidates. The last chapter discusses the regulatory perspectives of safety testing of drug metabolites and why, how, and when to test their safety.