This concise manual provides clinicians and other related health care professionals with an essential reference tool to the background of cystic fibrosis, and the management and treatment of this disease. The latest guidelines are reviewed and current and emerging treatments are discussed in the latter chapters. Cystic fibrosis is an inherited condition where a mutation in the gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR) causes loss of function. The dysfunction of CFTR results in the production of thick mucus in the lungs and digestive tract, causing pulmonary and gastrointestinal manifestations. The incidence of cystic fibrosis in Europe and the US ranges between 1 in 2,000 and 1 in 25,000.
|Publication date:||7th October 2016|
|Author:||Amy G. Filbrun, Amy Goldstein Filbrun, Clement L. Ren, Thomas Lahiri|
|Publisher:||Adis an imprint of Springer International Publishing AG|
|Categories:||Respiratory medicine, Gastroenterology,|
Amy G Filbrun, MD, MS, is Clinical Associate Professor of Pediatrics at University of Michigan and C.S. Mott Children's Hospital, in Ann Arbor, MI USA. She received her BS in Speech from Northwestern University and her MD from Ohio State University. She completed her pediatric residency at The Cleveland Clinic, in Cleveland, OH and fellowship in pediatric pulmonology at Columbus Children's Hospital (now Nationwide Children's Hospital) in Columbus, OH USA. She received her MS in Clinical Research Design and Statistical Analysis from University of Michigan. Her research interests include the evaluation of early childhood lung diseases, particularly measures of ...More About Amy G. Filbrun, Amy Goldstein Filbrun, Clement L. Ren, Thomas Lahiri