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Treatment and Prevention of Malaria Antimalarial Drug Chemistry, Action and Use

by Henry M. Staines

Part of the Milestones in Drug Therapy Series

Treatment and Prevention of Malaria Antimalarial Drug Chemistry, Action and Use Synopsis

Malaria has defeated previous efforts at eradication and remains a massive global public health problem despite being readily preventable and treatable. It is a devastating disease that also extracts huge economic costs from the poorest countries in endemic regions. Starting with an overview of the disease and its current political, financial and technical context, this Milestones in Drug Therapy volume describes the history, chemistry, mechanisms of action and resistance, preclinical and clinical use, pharmacokinetics and safety and tolerability of the current range of antimalarial drugs. There is particular emphasis on artemisinins and related peroxides, as these drugs have now become the frontline treatment for malaria. Next generation antimalarials, molecular markers for detecting resistance, the importance of diagnostics and disease prevention are also covered in detail.

Treatment and Prevention of Malaria Antimalarial Drug Chemistry, Action and Use Press Reviews

From the reviews: Staines and Krishna successfully captures the essence of what we know about antimalarials at the beginning of the second decade of the 21st century. ... the book is a welcome and highly valuable documentation on where we stand and offers valuable food for thought in the search for the way forward. (Martin P. Grobusch, Trends in Parasitology, September, 2012)

Book Information

ISBN: 9783034808088
Publication date: 22nd February 2014
Author: Henry M. Staines
Publisher: Springer Basel
Format: Paperback / softback
Pagination: 318 pages
Categories: Pharmacology, Infectious & contagious diseases, Medical parasitology, Immunology, Pharmacology,

About Henry M. Staines

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