The Serotonin Receptors From Molecular Pharmacology to Human Therapeutics

by Bryan L. Roth

Part of the The Receptors Series

The Serotonin Receptors From Molecular Pharmacology to Human Therapeutics Synopsis

A comprehensive, state-of-the-art review of our current understanding of the molecular and structural biology of 5-HT receptors and their potential use for drug discovery. The authors describe the anatomical, cellular, and subcellular distribution of 5-HT receptors and demonstrate a powerful approach to elucidating their physiological role using knockout mice in which the 5-HT receptors were deleted. They also review our understanding of the physiological role(s) of 5-HT receptors based mainly on studies performed in genetically engineered mice. Highlights include discussions of the behavioral phenotypes of 5-HT receptor knockout animals, the molecular biology and pharmacology of 5-HT receptors, and insights into the complexity of 5-HT receptor signal transduction.

The Serotonin Receptors From Molecular Pharmacology to Human Therapeutics Press Reviews

From the reviews: This is a compilation of reviews regarding various aspects of serotonin receptor structure and function. ... As a set of reviews, the book can be read by a broad scientific audience. Material of interest to senior scientists and research fellows is present. ... Investigators wishing an up-to-date review of this field will find this book valuable. Those with selected interest, whether evolutionary or structural, will also find useful material. ... is a good, comprehensive set of reviews. ... overall, it is a valuable book. (Eugene A Davidson, Doody's Review Service, February, 2007)

Book Information

ISBN: 9781617376474
Publication date: 28th October 2010
Author: Bryan L. Roth
Publisher: Humana Press Inc.
Format: Paperback
Pagination: 618 pages
Categories: Pharmacy / dispensing,

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