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Leukemias Principles and Practice of Therapy by Stefan H. Faderl

Leukemias Principles and Practice of Therapy


Leukemias Principles and Practice of Therapy by Stefan H. Faderl

Edited by experts from one of the world's largest leukemia centers, this book provides information on the biology of the variety of leukemic disorders, up-to-date diagnostic testing and many new developments in therapy. Chapters covering new treatments present an outlook for the future and explain the rationale for ongoing clinical trials. Topics include: * Targeted therapy, e.g. tyrosine kinase inhibitors (Flt3, Aurora kinase inhibitors, kit inhibitors, BCR-ABL inhibitors) * Ras inhibitors * Epigenetic therapy (hypomethylaters and histone deacetylase inhibitors) * Lenalidomide analogs * New chemotherapy drugs, e.g. clofarabine, cloretazine, sapacitabine, forodesine * Combinations of chemotherapy with kinase inhibitors (e.g. ALL induction protocols in combination with dasatinib or imatinib) * New monoclonal antibodies (lumiliximab, humaxCD20, anti-CD40) * Thrombopoietic agents Leukemias: Principles and Practice of Therapy * Includes practical information to guide you in challenging situations, such as treatment of elderly patients, pregnancy, relapsed and refractory disease * Incorporates chapters on supportive care and pharmacologic information about the most frequently used drugs in this area


This high quality book will be an excellent reference for both fellows and attending physicians who care for patients with leukemic disorders in either a community or academic setting ... This book is a welcome resource for those entering the field as well as for long-time practitioners who want to stay up to date. (Doody's, 12 August 2011)

About the Author

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Book Info

Publication date

23rd November 2010


Stefan H. Faderl

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Wiley-Blackwell (an imprint of John Wiley & Sons Ltd) an imprint of John Wiley and Sons Ltd


456 pages


Neurology & clinical neurophysiology
Medical imaging



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