Developed as a one-stop reference source for drug safety and toxicology professionals, this book explains why mitochondrial failure is a crucial step in drug toxicity and how it can be avoided. • Covers both basic science and applied technology / methods • Allows readers to understand the basis of mitochondrial function, the preclinical assessments used, and what they reveal about drug effects • Contains both in vitro and in vivo methods for analysis, including practical screening approaches for drug discovery and development • Adds coverage about mitochondrial toxicity underlying organ injury, clinical reports on drug classes, and discussion of environmental toxicants affecting mitochondria
ISBN: | 9781119329701 |
Publication date: | 11th May 2018 |
Author: | Yvonne Will |
Publisher: | John Wiley & Sons Inc |
Format: | Hardback |
Pagination: | 816 pages |
Genres: |
Medical toxicology |