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Interpreting Protein Mass Spectra A Comprehensive Resource by Peter Snyder

Interpreting Protein Mass Spectra A Comprehensive Resource

RRP £105.00


Interpreting Protein Mass Spectra A Comprehensive Resource by Peter Snyder

Interpreting Protein Mass Spectra is a hands-on laboratory guide for a wide range of researchers investigating the structures of proteins and peptides. The focus is on the interpretation of structural information gathered through electrospray ionization-mass spectrometry (ESI-MS). The book will also provide useful background and protocols for anyone using matrix-assisted laser desorption/ionization (MALDI), fast atom bombardment (FAB), and secondary ion mass spectrometry (SIMS). The book includes numerous practical examples, detailed discussions of experimental setups, and valuable hints for troubleshooting both methods and the handling of materials.


Mass spectrometry rather than protein mass is the concern of Snyder, a research chemist for the British Army. He explains his chosen methods for interpreting the primary structure of proteins as well as their post-translation modifications. He presents electrospray ionization- mass spectrometry (ESI-MS) as one of the more attractive tools for determining protein integrity and structure, but also outlines the use of high pressure liquid chromatography, capillary electrophoresis, and tandem mass spectrometry. Highlighting phosphoproteins and glycoproteins, he shows how to analyze separate peaks and details within a high mass peak, which give the purity, reproducibility, and signal optimization characteristics of the mass spectrum of a protein. He intends his treatment to be a course text for beginning graduate students and a reference for researchers. It was developed in partnership with the American Chemical Society. --SciTech Book News Those wishing to understand and, perhaps, interpret such macromolecular data will be well rewarded by using this as a study guide. -- Doody's

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Book Info

Publication date

31st August 2000


Peter Snyder

More books by Peter Snyder
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American Chemical Society


544 pages


Scientific equipment, experiments & techniques
Polymer chemistry
Analytical chemistry



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