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State-of-the-Art and Emerging Technologies for Therapeutic Monoclonal Antibody Characterization Volume 3. Defining the Next Generation of Analytical and Biophysical Techniques

by John E. (Research Chemist, NIST Biomolecular Measurement Division, Research Chemist, NIST Biomolecular Measurement Divi Schiel

Part of the ACS Symposium Series Series

State-of-the-Art and Emerging Technologies for Therapeutic Monoclonal Antibody Characterization Volume 3. Defining the Next Generation of Analytical and Biophysical Techniques Synopsis

This volume describes novel and emerging analytical technologies for analysis of proteins with the emphasis on technologies aimed to address characterization knowledge gaps and/or improve our ability to measure specified attributes with improved selectivity, sensitivity, resolution, and throughput. Higher order structure of proteins is a recognized important attribute of mAbs, with potential implications on stability, safety, and biological function of these large molecules. This book, the last in a series of three volumes, touches on topics ranging from X-ray crystallography, NMR, hydrogen-deuterium exchange mass spectrometry, covalent labeling techniques, and ion mobility mass spectrometry.

Book Information

ISBN: 9780841230316
Publication date: 1st September 2016
Author: John E. (Research Chemist, NIST Biomolecular Measurement Division, Research Chemist, NIST Biomolecular Measurement Divi Schiel
Publisher: Oxford University Press Inc
Format: Hardback
Pagination: 464 pages
Categories: Xenobiotics, Biochemistry,

About John E. (Research Chemist, NIST Biomolecular Measurement Division, Research Chemist, NIST Biomolecular Measurement Divi Schiel

Dr. John E. Schiel received his B.S. (2004) and Ph.D.(2009) in Chemistry from the University of Nebraska-Lincoln, and is currently a research chemist in the NIST Biomolecular Measurement Division. Dr. Darryl L. Davis holds a doctorate in Medicinal Chemistry from the Philadelphia College of Pharmacy and Science. Currently he leads an analytical group within the discovery organization at Janssen R&D. Dr. Oleg V. Borisov earned a B.S. degree (with honors) in Chemistry at Moscow State University (1992), and received his Ph.D. in Chemistry from Wayne State University (1997), after which he completed his post-doctoral studies at Lawrence Berkeley ...

More About John E. (Research Chemist, NIST Biomolecular Measurement Division, Research Chemist, NIST Biomolecular Measurement Divi Schiel

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