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Preclinical Research in Down Syndrome: Insights for Pathophysiology and Treatments

by Mara (CRG-Center for Genomic Regulation, Spain) Dierssen

Preclinical Research in Down Syndrome: Insights for Pathophysiology and Treatments Synopsis

Preclinical Research in Down Syndrome: From Bench to Bedside, Volume 251, the latest release in the Progress in Brain Research series, highlights new advances in the field. Chapters in this updated release include Exploring genetic and epigenetic mechanisms underlying cognitive deficits in Dow syndrome, The trisomy paradox: gene expression dysregulation domains, the Influence of allelic differences in mouse models of Down syndrome, Modelling Down syndrome in cells: From stem cells to organoids, Modelling Down syndrome in animals from the early stage to the new generation of models, Mapping behavioral landscapes in Down syndrome animal models, and more.

Book Information

ISBN: 9780444642561
Publication date: 11th February 2020
Author: Mara (CRG-Center for Genomic Regulation, Spain) Dierssen
Publisher: Elsevier Science Ltd an imprint of Elsevier Science & Technology
Format: Hardback
Pagination: 318 pages
Categories: Neurosciences, Physiological & neuro-psychology, biopsychology,

About Mara (CRG-Center for Genomic Regulation, Spain) Dierssen

Mara Dierssen is a Doctor in Medicine and Surgery from the University of Cantabria, (1989). She leads the Cellular and Systems Neurobiology laboratory at the Genomic Regulation Center (CRG) and is associate researcher of the Hospital del Mar Research Institute, where she promoted the creation of a translational research program to study new therapeutic approaches in intellectual disability. Her main current scientific interests are focused on the study of the neurobiological mechanisms underlying memory and learning and their alteration in complex diseases (polygenic and multifactorial) and in the development and application of this knowledge to the field of clinical practice. Among ...

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