Maxim Jakubowskis Selection win prizes eleanor oliphant Harry Potter House Eds likeyoulove
Search our site
The Good Daughter by Karin Slaughter Read the opening extract of the brand new Karin Slaughter book before its publication on 13/07/2017

Infectious Behavior Brain-Immune Connections in Autism, Schizophrenia, and Depression by Paul H. (Anne P. and Benjamin F. Biaggini Professor of Biological Sciences, California Institute of Technology) Patterson
  

Infectious Behavior Brain-Immune Connections in Autism, Schizophrenia, and Depression

,

Part of the Infectious Behavior Series

RRP £13.95

Synopsis

Infectious Behavior Brain-Immune Connections in Autism, Schizophrenia, and Depression by Paul H. (Anne P. and Benjamin F. Biaggini Professor of Biological Sciences, California Institute of Technology) Patterson

In Infectious Behavior, neurobiologist Paul Patterson examines the involvement of the immune system in autism, schizophrenia, and major depressive disorder. Although genetic approaches to these diseases have garnered the lion's share of publicity and funding, scientists are uncovering evidence of the important avenues of communication between the brain and the immune system and their involvement in mental illness. Patterson focuses on this brain-immune crosstalk, exploring the possibility that it may help us understand the causes of these common, but still mysterious, diseases. The heart of this engaging book, accessible to nonscientists, concerns the involvement of the immune systems of the pregnant woman and her fetus, and a consideration of maternal infection as a risk factor for schizophrenia and autism. Patterson reports on research that may shed light on today's autism epidemic. He also outlines the risks and benefits of both maternal and postnatal vaccinations.In the course of his discussion, Patterson offers a short history of immune manipulation in treating mental illness (recounting some frightening but fascinating early experiments) and explains how the immune system influences behavior and how the brain regulates the immune system, looking in particular at stress and depression. He examines the prenatal origins of adult disease and evidence for immune involvement in autism, schizophrenia, and depression. Finally, he describes the promise shown by recent animal experiments that have led to early clinical trials of postnatal and adult treatments for patients with autism and related disorders.

Reviews

A chapter is devoted to an evidence-based review of the theory of a connection between vaccinations and autism. For this chapter alone, this book is worth a recommendation. This well-written book is good for anyone interested in behavior, disease, maternal-child health, and public health. * Library Journal * His title is a little daunting, but neurobiologist Patterson has succeeded in his aim of crafting an accessible, even fascinating, book about one of the hottest topics in mental health. In the long-running nature versus nurture argument, our era is all about nature. There is no one left -- no one with scientific credentials, at least -- who believes the way we nurture our offspring (cold mothers, distant fathers) creates autistic or schizophrenic children. But nature for too many people, experts and laypersons alike, means our genes alone. And they, Patterson shows, are not the whole story. He notes how the final health effects from the great flu pandemic of 1918, which killed more people than the Great War, played out very recently. Those who were in their mothers
wombs during the pandemic went on to a lifetime of health and socio

-economic problems disproportionately worse than those of children born before or after: lower educational achievement and lower incomes, higher rates of diabetes and heart disease. Those outcomes are suggestive of the virus's effect on fetal brain development; the fact they often did not appear before adulthood supports the emerging hypothesis of the fetal origins of many adult diseases. Patterson describes the womb as a 'battlefield,
in which a fetus has to struggle to fend off rejection by the mother

's immune system. Infection, which ramps up the immune response, can have devastating effects on fetal brains. The latest studies indicate that the risk of schizophrenia among the male offspring of women who come down with the flu during the first half of their pregnancies is three to seven times higher than usual. Patterson notes that common-sense ways to cut down on flu infection are widely known -- wash your hands and avoid airplane flights if at all possible -- but often ignored, even by pregnant women, because the stakes seem so small. He's done his best to correct that assumption. * Macleans * Neurobiologist Paul Patterson, PhD, has produced a remarkably accessible and enjoyable book that intertwines history, case studies and laboratory science...It's an engaging and thought-provoking read for nonscientists and scientists alike. * Autism Speaks blog * For the non-expert, this field can be more intimidating than a box of jumbled Christmas decorations. In Infectious Behavior: Brain-Immune Connections in Autism, Schizophrenia, and Depression, biologist Paul Patterson nimbly untangles the strings of lights. -- Virginia Hughes, Simons Foundation Autism Research Initiative The book is simultaneously accessible to the lay reader and insightful to the reader with more expertise. It flows like a professor who rolls up his sleeves and delivers an engaging talk to his audience without once looking at his slides. [It] is a well written, enjoyable read for any audience. * Brain, Behavior, and Immunity * Patterson's book is so clear and compelling that it will appeal to clinicians awaiting novel disease models with new opportunities for prevention and cure, family members endlessly pondering the source of their loved one's ailment, and any reader who enjoys medical detective stories. A lucid synthesis of historical and current thinking about 'infectious'
routes to mental illness

. * American Journal of Psychiatry *


About the Author

Paul H. Patterson, a developmental neurobiologist, is Anne P. and Benjamin R. Biaggini Professor of Biological Sciences at the California Institute of Technology and a Research Professor of Neurological Surgery at the University of Southern California's Keck School of Medicine. He is the coauthor (with Alan Brown) of The Origins of Schizophrenia.

More books by this author
Author 'Like for Like' recommendations

Loading other formats...

Book Info

Publication date

13th September 2013

Author

Paul H. (Anne P. and Benjamin F. Biaggini Professor of Biological Sciences, California Institute of Technology) Patterson

More books by Paul H. (Anne P. and Benjamin F. Biaggini Professor of Biological Sciences, California Institute of Technology) Patterson
Author 'Like for Like'
    recommendations

Publisher

MIT Press an imprint of MIT Press Ltd

Format

Paperback
176 pages

Categories

Autism & AspergerÍs Syndrome
Immunology
Neurosciences

ISBN

9780262525343

I love reading books I wouldn't normally choose before everyone else gets to read them!

Dawn Lynch

Lovereading is an amazing place to be, the website is wonderful and to me if I'm sad I'll go here and it cheers me up!

Sophia Upton

It is a website dedicated to those who adore reading It really is a one stop shop for book lovers. Love it!

Edel Waugh

Lovereading does a stella job in promoting both new and established authors.

Iris Clements

I read new, exciting writers and established authors before publication and there is a great website full of brilliant books and opinions.

Lynda

As for why I'd recommend Lovereading, it's simple - it's a great place to get information and reviews about new books!

Margaret Freeman

I love the honest opinions, recommendations for every genre and every reader, wish lists and Like for Like.

Amrita Dasgupta

Books of the month/debuts of the month, kids/adults, fiction/non-fiction, free prize draws and free extracts, what's not to love?

Emma Smith

Lovereading4kids

Lovereading4schools