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The Organic Chemistry of Drug Design and Drug Action, Third Edition, represents a unique approach to medicinal chemistry based on physical organic chemical principles and reaction mechanisms that rationalize drug action, which allows reader to extrapolate those core principles and mechanisms to many related classes of drug molecules. This new edition includes updates to all chapters, including new examples and references. It reflects significant changes in the process of drug design over the last decade and preserves the successful approach of the previous editions while including significant changes in format and coverage. This text is designed for undergraduate and graduate students in chemistry studying medicinal chemistry or pharmaceutical chemistry; research chemists and biochemists working in pharmaceutical and biotechnology industries.
|Publication date:||21st May 2014|
|Author:||Richard B. (Northwestern University, Evanston, IL, USA) Silverman, Mark W. (Ambit Biosciences, San Diego, CA, USA) Holladay|
|Publisher:||Academic Press Inc an imprint of Elsevier Science Publishing Co Inc|
|Categories:||Pharmaceutical technology, Organic chemistry,|
Professor Richard B. Silverman received his B.S. degree in chemistry from The Pennsylvania State University in 1968 and his Ph.D. degree in organic chemistry from Harvard University in 1974 (with time off for a two-year military obligation from 1969-1971). After two years as a NIH postdoctoral fellow in the laboratory of the late Professor Robert Abeles in the Graduate Department of Biochemistry at Brandeis University, he joined the chemistry faculty at Northwestern University. In 1986, he became Professor of Chemistry and Professor of Biochemistry, Molecular Biology, and Cell Biology. In 2001, he became the Charles Deering McCormick Professor of Teaching Excellence for ...More About Richard B. (Northwestern University, Evanston, IL, USA) Silverman, Mark W. (Ambit Biosciences, San Diego, CA, USA) Holladay