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This book serves as a current resource for Photoplethysmogram (PPG) signal analysis using MATLAB (R). This technology is critical in the evaluation of medical and diagnostic data utilized in mobile devices. Information and methodologies outlined in the text can be used to learn the empirical and experimental process (including data collection, data analysis, feature extractions, and more) from inception to conclusion. This book also discusses how introduced methodologies can be used and applied as tools that will teach the user how to validate, test, and simulate developed algorithms before implementing and deploying the algorithms on wearable, battery-driven, or point-of-care devices.