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This book presents the survismeter, a new invention that widely covers and determines PCPs of various molecules and experimentally measures the thermodynamic and kinetic stabilities of nanoemulsions. It unveils how a survismeter can measure surface tension, interfacial tension, wettability, viscosity, friccohesity, tentropy, rheology, density, activation energy, and particle size. It discusses novel models of molecular science that can be applied in the formulation and study of activities of functional molecules through their PCPs. It also introduces the new concept of friccohesity, which has emerged as an excellent substitute of viscosity and surface tension in experimental measurements as it does not require density measurements. It shows that the science and technology of the survismeter and friccohesity have become an inevitable part of scientific research, substantially integrating the domain of perfect industrial and academic formulations.
Although serious interest in studying the role of central cho linergic processes in psychopathology is just beginning to emerge, experimental literature on the part played by cholinergic mechanisms in brain behavior. reiations is quite extensive. During the past thirty years, cholinergic research has contributed significantly to the characterization and differentiation of adaptive mechanisms in volved in input selection, perception, cortical, autonomic and behav ioral activation, learning, memory, and inhibitory control of behav ioral outputs. To say that dysfunction of one or more of these mech anisms may be at the root of neuropsychiatric illnesses such as schiz ophrenia would be stating the obvious. This book examines the part cholinergic processes might play in dysfunctions of the adaptive processes involved in higher brain func tions and their significance for the pathogenesis, classification, etiology, and treatment of psychopathological conditions. In a series of wide ranging reviews of the available information, the subject is discussed from a variety of perspectives, using data derived from both experimental and clinical research. The purpose is not so much to determine whether cholinergic excess or deficiency is causal in this or that neuropsychiatric syndrome, but rather to try to understand the disease mechanisms in terms of adaptive processes in which cholinergic systems seem to play an important part.